STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17378.1Transcriptional regulator, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060: IPR009594: IPR000005; KEGG: dma:DMR_01320 AraC family transcriptional regulator; PFAM: AraC-type transcriptional regulator domain protein; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-type transcriptional regulator N-terminus. (297 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.860
ADW17379.1
Iron-containing alcohol dehydrogenase; COGs: COG1979 Uncharacterized oxidoreductase Fe-dependent alcohol dehydrogenase family; InterPro IPR001670; KEGG: gbm:Gbem_0781 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase.
 
     0.620
ADW18442.1
Transcriptional regulator, XRE family; COGs: COG0467 RecA-superfamily ATPase implicated in signal transduction; InterPro IPR001387: IPR013096; KEGG: sfu:Sfum_4068 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; PFAM: Cupin domain; Helix-turn-helix.
 
 
 0.530
ADW18389.1
COGs: COG4786 Flagellar basal body rod protein; InterPro IPR001444: IPR010930: IPR020013; KEGG: dps:DP2680 flagellar basal-body rod protein (FlgF); PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; SPTR: Related to flagellar basal-body rod protein (FlgF); TIGRFAM: flagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; flagellar hook-basal body proteins.
    
   0.516
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.476
ADW17951.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284: IPR007127: IPR009042: IPR007627: IPR 007624: IPR007630: IPR000943; KEGG: dps:DP2503 RNA polymerase sigma factor (RpoD); PFAM: sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 factor, region 1.1; Sigma-70 region 3; Sigma- [...]
    
 
 0.446
ADW19069.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.446
ADW17377.1
Diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767; KEGG: pca:Pcar_2296 GGDEF domain-containing protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: FOG: GGDEF domain protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
  
  
 0.424
ADW16450.1
Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107: IPR002104; KEGG: cpr:CPR_1179 site-specific tyrosine recombinase XerC; PFAM: integrase family protein; integrase domain protein SAM domain protein; SPTR: Site-specific recombinase, phage integrase family; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family.
  
  
 0.422
ADW17554.1
Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: dba:Dbac_1025 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family.
  
   
 0.404
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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