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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ADW17419.1Thioredoxin domain-containing protein; InterPro IPR017936: IPR013766; KEGG: dal:Dalk_4731 thioredoxin domain protein; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin domain protein; PFAM: Thioredoxin. (131 aa)    
Predicted Functional Partners:
ADW17420.1
InterPro IPR003834; KEGG: dde:Dde_2782 hypothetical protein; PFAM: cytochrome c biogenesis protein transmembrane region; SPTR: Putative uncharacterized protein; PFAM: Cytochrome C biogenesis protein transmembrane region.
 
 
 0.990
ADW18078.1
COGs: COG0225 Peptide methionine sulfoxide reductase; InterPro IPR002569: IPR002579; KEGG: tau:Tola_0999 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; Methionine sulfoxide reductase A; PRIAM: Peptide-methionine (S)-S-oxide reductase., Peptide-methionine (R)-S-oxide reductase; SPTR: Methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; peptide methionine sulfoxide reductase; PFAM: SelR domain; Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase.
   
 0.985
ADW16737.1
Protein-disulfide reductase; COGs: COG4232 Thiol:disulfide interchange protein; InterPro IPR003834; KEGG: sfu:Sfum_3483 cytochrome c biogenesis protein, transmembrane region; PFAM: cytochrome c biogenesis protein transmembrane region; PRIAM: Protein-disulfide reductase; SPTR: Cytochrome c biogenesis protein, transmembrane region; PFAM: Cytochrome C biogenesis protein transmembrane region.
 
 
 0.903
ADW19439.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG0450 Peroxiredoxin; InterPro IPR000866: IPR019479: IPR017936; KEGG: gsu:GSU3246 thioredoxin peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like; SPTR: Thioredoxin peroxidase; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
  
 0.898
ADW17100.1
Peptidylprolyl isomerase; COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130: IPR001179: IPR020892; KEGG: dps:DP1645 peptidyl-prolyl cis-trans isomerase; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; peptidylprolyl isomerase FKBP-type; PRIAM: Peptidylprolyl isomerase; SPTR: Probable peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD.
    
 
 0.894
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
 0.891
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.843
ADW17418.1
DGC domain protein; COGs: COG4273 conserved hypothetical protein; InterPro IPR014958; KEGG: dps:DP0947 hypothetical protein; PFAM: DGC domain protein; SPTR: Putative uncharacterized protein; PFAM: DGC domain.
 
    0.836
ADW17801.1
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR005746: IPR013766: IPR017936: IPR017937; KEGG: dal:Dalk_0228 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin.
 
  
 0.783
ADW17793.1
Thioredoxin domain-containing protein; InterPro IPR013766: IPR017936: IPR017937; KEGG: cfe:CF0924 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; PFAM: Thioredoxin.
 
  
 0.740
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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