Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW17439.1Arsenite efflux ATP-binding protein ArsA; COGs: COG0003 ATPase involved in chromosome partitioning; InterPro IPR003348: IPR016300: IPR003593; KEGG: psa:PST_0237 arsenical pump-driving ATPase; PRIAM: Arsenite-transporting ATPase; SPTR: Arsenical pump-driving ATPase; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase (arsA); TC 3.A.4.1.1. (600 aa)    
Predicted Functional Partners:
ADW19398.1
AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959: IPR003593; KEGG: aeh:Mlg_1753 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; PFAM: ATPase family associated with various cellular activities (AAA).
  
 
 0.775
ADW16769.1
COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR014732: IPR001754: IPR018089; KEGG: dak:DaAHT2_2202 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 1.
    
   0.759
ADW17878.1
COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR011995: IPR001754: IPR018089; KEGG: cja:CJA_3170 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2.
    
   0.759
ADW16251.1
Na+/Ca+ antiporter, CaCA family; COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004481: IPR004837; KEGG: cli:Clim_1218 Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; SPTR: K+-dependent Na+/Ca+ exchanger related-protein; TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein.
   
   0.715
ADW18535.1
COGs: COG0060 Isoleucyl-tRNA synthetase; InterProIPR015905: IPR002300: IPR013155: IPR010663: IPR 001412: IPR002301; KEGG: dps:DP2552 isoleucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: Isoleucyl-tRNA synthetase; TIGRFAM: isoleucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Zinc finger found in FPG and IleRS; TIGRFAM: isoleucyl-tRNA synthetase.
    
   0.715
ADW18923.1
COGs: COG0194 Guanylate kinase; InterPro IPR008144: IPR017665: IPR020590: IPR008145; KEGG: dak:DaAHT2_0280 guanylate kinase; PFAM: guanylate kinase; PRIAM: Guanylate kinase; SMART: guanylate kinase/L-type calcium channel region; SPTR: Guanylate kinase; TIGRFAM: guanylate kinase; PFAM: Guanylate kinase; TIGRFAM: guanylate kinase.
    
   0.710
ADW17409.1
Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: tbd:Tbd_1428 arsenite S-adenosylmethyltransferase; PFAM: Methyltransferase type 11; SPTR: UbiE/COQ5 methyltransferase; PFAM: Methyltransferase domain.
 
    
 0.695
ADW17438.1
Hypothetical protein; KEGG: dal:Dalk_1610 putative PAS/PAC sensor protein; SPTR: Response regulator receiver protein.
  
    0.682
ADW17437.1
Transcriptional regulator, ArsR family; InterPro IPR001845; KEGG: yen:YE3478 hypothetical protein; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Putative uncharacterized protein; PFAM: Bacterial regulatory protein, arsR family.
     
 0.589
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.474
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.