Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17456.1Pyridoxine 5'-phosphate synthase; COGs: COG0854 Pyridoxal phosphate biosynthesis protein; InterPro IPR002036: IPR004569: IPR020549; KEGG: dps:DP1605 pyridoxal phosphate biosynthetic protein; PFAM: Pyridoxal phosphate biosynthetic protein PdxJ; protein of unknown function UPF0054; PRIAM: Pyridoxine 5'-phosphate synthase; SPTR: Probable pyridoxal phosphate biosynthetic protein; TIGRFAM: pyridoxal phosphate biosynthetic protein PdxJ; PFAM: Pyridoxal phosphate biosynthesis protein PdxJ; Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family; pyridoxine 5'-phos [...] (392 aa)    
Predicted Functional Partners:
ADW17457.1
PhoH family protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: dps:DP1606 phosphate starvation-induced protein; PFAM: PhoH family protein; SPTR: Probable phosphate starvation-induced protein; PFAM: PhoH-like protein.
  
  
 0.989
ADW17141.1
GTP-binding protein Era; COGs: COG1159 GTPase; InterProIPR006073: IPR004044: IPR002917: IPR005662: IPR 005225; KEGG: dps:DP1689 GTP-binding protein Era-like protein; PFAM: GTP-binding protein HSR1-related; KH type 2 domain protein; SPTR: GTP-binding protein era homolog; TIGRFAM: GTP-binding protein Era; small GTP-binding protein; PFAM: KH domain; GTPase of unknown function; TIGRFAM: GTP-binding protein Era; small GTP-binding protein domain.
 
  
 0.951
ADW18108.1
COGs: COG0259 Pyridoxamine-phosphate oxidase; InterPro IPR000659: IPR019740: IPR011576: IPR019576; KEGG: maq:Maqu_0155 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; Pyridoxine 5'-phosphate oxidase, dimerisation-like; PRIAM: Pyridoxal 5'-phosphate synthase; SPTR: Pyridoxine/pyridoxamine 5'-phosphate oxidase; TIGRFAM: pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase; Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; TIGRFAM: pyridoxamine-phosphate oxidase.
  
  
 0.940
ADW17277.1
Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: dak:DaAHT2_0193 rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.
  
 
 0.894
ADW18523.1
4-hydroxythreonine-4-phosphate dehydrogenase; COGs: COG1995 Pyridoxal phosphate biosynthesis protein; InterPro IPR005255; KEGG: dak:DaAHT2_1165 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase.
 
  
 0.886
ADW18043.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterProIPR020845: IPR009081: IPR006163: IPR000873: IPR 002123; KEGG: ppr:PBPRB0014 acyltransferase family protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: Hypothetical acyltransferase family protein; PFAM: Phosphopantetheine attachment site; Acyltransferase; AMP-binding enzyme; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
   
 
 0.884
ADW16901.1
InterPro IPR002917; KEGG: dat:HRM2_21850 FusA1; PFAM: GTP-binding protein HSR1-related; SPTR: FusA1; PFAM: GTPase of unknown function; Domain of unknown function (DUF3482).
  
  
 0.876
ADW17909.1
COGs: COG0605 Superoxide dismutase; InterPro IPR019831: IPR019832: IPR001189: IPR019833; KEGG: efa:EF0463 superoxide dismutase, Mn; PFAM: Manganese/iron superoxide dismutase-like; PRIAM: Superoxide dismutase; SPTR: Superoxide dismutase; PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain.
    
 
 0.862
ADW17458.1
DSBA oxidoreductase; COGs: COG1651 Protein-disulfide isomerase; InterPro IPR017936: IPR001853; KEGG: dps:DP1607 27kDa outer membrane protein; PFAM: DSBA oxidoreductase; SPTR: Related to 27kDa outer membrane protein; PFAM: DSBA-like thioredoxin domain.
  
   0.841
rplQ
COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: dak:DaAHT2_1424 ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; manually curated; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17.
   
 
 0.836
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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