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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ADW17459.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; InterPro IPR013344: IPR013509: IPR000788; KEGG: dps:DP2827 ribonucleoside-diphosphate reductase; PFAM: ribonucleotide reductase large subunit; Ribonucleotide reductase large subunit domain protein; PRIAM: Ribonucleoside-diphosphate reductase; SPTR: Ribonucleoside-diphosphate reductase; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: Ribonucleotide reductase, all-alpha domain; Ribonucleotide reductase, barrel domain; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent. (723 aa)    
Predicted Functional Partners:
ADW18522.1
COGs: COG0125 Thymidylate kinase; InterPro IPR018094: IPR000062: IPR018095; KEGG: dak:DaAHT2_1164 thymidylate kinase; PFAM: thymidylate kinase; PRIAM: dTMP kinase; SPTR: Thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase.
  
 
 0.946
ADW19434.1
COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: dak:DaAHT2_2673 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
  
 
 0.926
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 0.924
ADW17767.1
Protein of unknown function DUF179; COGs: COG1678 Putative transcriptional regulator protein; InterPro IPR003774; KEGG: dak:DaAHT2_1057 protein of unknown function DUF179; PFAM: protein of unknown function DUF179; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1678.
   
 0.922
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.920
ADW18923.1
COGs: COG0194 Guanylate kinase; InterPro IPR008144: IPR017665: IPR020590: IPR008145; KEGG: dak:DaAHT2_0280 guanylate kinase; PFAM: guanylate kinase; PRIAM: Guanylate kinase; SMART: guanylate kinase/L-type calcium channel region; SPTR: Guanylate kinase; TIGRFAM: guanylate kinase; PFAM: Guanylate kinase; TIGRFAM: guanylate kinase.
     
 0.908
ADW17001.1
(p)ppGpp synthetase I, SpoT/RelA; COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR006674: IPR007685: IPR004095: IPR004811: IPR 000408; KEGG: dps:DP1165 GTP pyrophosphokinase; PFAM: RelA/SpoT domain protein; metal-dependent phosphohydrolase HD sub domain; TGS domain-containing protein; PRIAM: GTP diphosphokinase; SPTR: Probable GTP pyrophosphokinase; TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain; Region found in RelA / SpoT proteins; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family.
   
 
  0.902
ADW18725.1
(p)ppGpp synthetase I, SpoT/RelA; COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterPro IPR003607: IPR006674: IPR007685: IPR004095; KEGG: dps:DP1905 GTP pyrophosphokinase; PFAM: TGS domain-containing protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; PRIAM: GTP diphosphokinase; SMART: metal-dependent phosphohydrolase HD region; SPTR: Probable GTP pyrophosphokinase; PFAM: HD domain; Region found in RelA / SpoT proteins; TGS domain; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family.
   
 
  0.902
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
  
 
 0.893
ADW18295.1
Glutaredoxin; COGs: COG4802 Ferredoxin-thioredoxin reductase catalytic subunit; InterPro IPR002109; KEGG: dps:DP2155 ferredoxin-thioredoxin reductase; PFAM: glutaredoxin; SPTR: Probable ferredoxin-thioredoxin reductase; PFAM: Glutaredoxin; Ferredoxin thioredoxin reductase catalytic beta chain.
 
 0.876
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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