STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17464.1InterPro IPR000644; KEGG: sat:SYN_01241 CBS domain-containing protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Cbs domain containing protein; PFAM: CBS domain. (150 aa)    
Predicted Functional Partners:
ADW16731.1
dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR005888: IPR001509: IPR020904; KEGG: dar:Daro_1237 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase.
  
    0.703
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
   
   0.686
ADW17465.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014: IPR005467: IPR001789: IPR000700: IPR 013656: IPR003594: IPR004358; KEGG: dma:DMR_27290 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATP [...]
   
   0.603
ADW17466.1
COGs: COG1639 signal transduction protein; InterPro IPR014626: IPR001789: IPR013976; KEGG: dma:DMR_38790 response regulator receiver protein; PFAM: Metal-dependent hydrolase HDOD; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: Response regulator receiver domain; HDOD domain.
   
   0.603
ADW17467.1
COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789; KEGG: sat:SYN_01373 hydrogenase transcriptional regulatory protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Hydrogenase transcriptional regulatory protein; PFAM: Response regulator receiver domain.
       0.574
ADW17463.1
Hypothetical protein; KEGG: dre:556925 regulatory factor X, 6; SPTR: Predicted protein.
       0.554
ADW18045.1
KEGG: mca:MCA0716 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
   0.516
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.496
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.468
ADW16679.1
COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR017926: IPR010073: IPR000728: IPR010918; KEGG: dps:DP0704 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Probable phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synt [...]
     
 0.464
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.