Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW17510.1COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000644; KEGG: dps:DP0350 hypothetical protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: CBS domain. (136 aa)    
Predicted Functional Partners:
ADW17511.1
InterPro IPR002187; KEGG: dps:DP0349 nitrogen regulatory protein P-II family proteins; SPTR: Nitrogen regulatory protein P-II; PFAM: Nitrogen regulatory protein P-II.
 
    0.927
ADW17512.1
Protein of unknown function DUF1538; InterPro IPR011435; KEGG: dps:DP0348 hypothetical protein; PFAM: protein of unknown function DUF1538; SPTR: Conserved hypothetical membrane protein; PFAM: Protein of unknown function (DUF1538).
 
     0.911
ADW17513.1
Protein of unknown function DUF1538; InterPro IPR011435; KEGG: dps:DP0347 major facilitator superfamily permease; PFAM: protein of unknown function DUF1538; SPTR: Probable permease of the major facilitator superfamily; PFAM: Protein of unknown function (DUF1538).
 
     0.907
ADW17509.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037: IPR013099: IPR003091; KEGG: dvm:DvMF_1148 TrkA-N domain protein; PFAM: TrkA-N domain protein; Ion transport 2 domain protein; TrkA-C domain protein; SPTR: TrkA-N domain protein; PFAM: TrkA-N domain; Ion channel; TrkA-C domain.
       0.547
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.463
ADW18052.1
Protein of unknown function DUF299; COGs: COG1806 conserved hypothetical protein; InterPro IPR005177; KEGG: dak:DaAHT2_1038 protein of unknown function DUF299; PFAM: protein of unknown function DUF299; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF299).
  
  
 0.461
ADW19022.1
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: cja:CJA_3147 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.453
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (18%) [HD]