Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17525.1COGs: COG0602 Organic radical activating protein; InterPro IPR007197; KEGG: dak:DaAHT2_0939 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM; PFAM: Radical SAM superfamily. (223 aa)    
Predicted Functional Partners:
ADW17526.1
preQ(0) biosynthesis protein QueD; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: dak:DaAHT2_0938 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
 
 
 0.999
ADW19282.1
preQ(0) biosynthesis protein QueC; COGs: COG0603 PP-loop superfamily ATPase; InterPro IPR018317: IPR004479; KEGG: dak:DaAHT2_2366 ExsB protein; PFAM: Queuosine synthesis-like; SPTR: ExsB; TIGRFAM: exsB protein; PFAM: ExsB; TIGRFAM: exsB protein.
 
 
 0.997
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.556
ADW17527.1
COGs: COG4123 O-methyltransferase; InterPro IPR007848: IPR002052; KEGG: dps:DP2267 hypothetical protein; PFAM: methyltransferase small; SPTR: Putative uncharacterized protein; PFAM: Methyltransferase small domain.
     
 0.531
ADW17524.1
Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014026: IPR014027; KEGG: vex:VEA_001773 UDP-glucose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: UDP-glucose dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP bin [...]
       0.523
ADW17528.1
Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482: IPR001208: IPR000523: IPR003593; KEGG: dak:DaAHT2_1394 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: Putative enzyme (N-terminal); transcriptional regulator with P-loop containing NTP hydrolase domain (C-terminal)(YifB); TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein.
       0.512
ADW17769.1
Protein of unknown function DUF163; COGs: COG1576 conserved hypothetical protein; InterPro IPR003742; KEGG: dak:DaAHT2_0704 protein of unknown function DUF163; PFAM: protein of unknown function DUF163; SPTR: Putative uncharacterized protein; PFAM: Predicted SPOUT methyltransferase; TIGRFAM: rRNA large subunit m3Psi methyltransferase RlmH.
   
    0.498
ADW16215.1
tRNA-guanine transglycosylase; COGs: COG0343 Queuine/archaeosine tRNA-ribosyltransferase; InterPro IPR004803: IPR002616; KEGG: dak:DaAHT2_1914 queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: Queuine tRNA-ribosyltransferase; TIGRFAM: queuine tRNA-ribosyltransferase; tRNA-guanine transglycosylase, various specificities; PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming.
     
 0.464
ADW18915.1
COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); InterPro IPR003699; KEGG: dak:DaAHT2_0258 S-adenosylmethionine/tRNA-ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR: Queuosine biosynthesis protein; TIGRFAM:S-adenosylmethionine/tRNA-ribosyltransferas e-isomerase; PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase.
   
  
 0.407
ADW19427.1
Protein of unknown function DUF208; COGs: COG1636 conserved hypothetical protein; InterPro IPR003828; KEGG: dak:DaAHT2_1640 protein of unknown function DUF208; PFAM: protein of unknown function DUF208; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized BCR, COG1636.
     
 0.402
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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