Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Score
ADW17526.1preQ(0) biosynthesis protein QueD; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: dak:DaAHT2_0938 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein. (122 aa)    
Predicted Functional Partners:
ADW17525.1
COGs: COG0602 Organic radical activating protein; InterPro IPR007197; KEGG: dak:DaAHT2_0939 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM; PFAM: Radical SAM superfamily.
 
 
 0.999
ADW19282.1
preQ(0) biosynthesis protein QueC; COGs: COG0603 PP-loop superfamily ATPase; InterPro IPR018317: IPR004479; KEGG: dak:DaAHT2_2366 ExsB protein; PFAM: Queuosine synthesis-like; SPTR: ExsB; TIGRFAM: exsB protein; PFAM: ExsB; TIGRFAM: exsB protein.
 
  
 0.976
ADW18963.1
GTP cyclohydrolase I; COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: dak:DaAHT2_0489 protein of unknown function DUF198; PFAM: protein of unknown function DUF198; PRIAM: GTP cyclohydrolase I; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1469.
 
  
 0.941
ADW18117.1
GTP cyclohydrolase I; COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: dak:DaAHT2_1707 protein of unknown function DUF198; PFAM: protein of unknown function DUF198; PRIAM: GTP cyclohydrolase I; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1469.
 
  
 0.930
ADW17704.1
COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: dma:DMR_08520 alkaline phosphatase precursor; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase.
     
  0.900
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
   
   0.605
ADW17524.1
Nucleotide sugar dehydrogenase; COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476: IPR001732: IPR014026: IPR014027; KEGG: vex:VEA_001773 UDP-glucose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: UDP-glucose dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP bin [...]
       0.564
ADW17528.1
Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482: IPR001208: IPR000523: IPR003593; KEGG: dak:DaAHT2_1394 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: Putative enzyme (N-terminal); transcriptional regulator with P-loop containing NTP hydrolase domain (C-terminal)(YifB); TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein.
       0.549
ADW17527.1
COGs: COG4123 O-methyltransferase; InterPro IPR007848: IPR002052; KEGG: dps:DP2267 hypothetical protein; PFAM: methyltransferase small; SPTR: Putative uncharacterized protein; PFAM: Methyltransferase small domain.
  
    0.539
ADW19311.1
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR001926: IPR015803: IPR015273: IPR005856: IPR 002308: IPR001216; KEGG: dal:Dalk_3820 cysteine synthase; PFAM: Cysteinyl-tRNA synthetase class Ia; Pyridoxal-5'-phosphate-dependent protein beta subunit; Cysteinyl-tRNA synthetase class Ia DALR; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases; cysteinyl-tRNA synthetase; cysteine synthase B.
  
  
 0.503
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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