STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Coexpression
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[Homology]
Score
ADW17632.1Response regulator receiver protein; COGs: COG0466 ATP-dependent Lon protease; InterProIPR001789: IPR003959: IPR003593: IPR001984: IPR 008268; KEGG: dma:DMR_10810 ATP-dependent protease Lon; PFAM: AAA ATPase central domain protein; response regulator receiver; SMART: response regulator receiver; AAA ATPase; SPTR: ATP-dependent protease Lon; PFAM: Response regulator receiver domain; ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La. (715 aa)    
Predicted Functional Partners:
ADW17968.1
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207: IPR003594: IPR002545: IPR001789: IPR 004105: IPR004358: IPR005467; KEGG: dps:DP2642 Che family two-component system sensory/regulatory protein; PFAM: ATP-binding region ATPase domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; response regulator receiver; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; response regulator receiver; SPTR: Related to two-component [...]
  
 
 0.918
ADW18423.1
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR005467: IPR001789: IPR002545: IPR008207: IPR 003594: IPR004358: IPR004105; KEGG: dps:DP2642 Che family two-component system sensory/regulatory protein; PFAM: ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; CheW domain protein; response regulator receiver; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; response regulator receiver; SPTR: Related to two-component [...]
  
 
 0.918
ADW18377.1
Surface presentation of antigens (SPOA) protein; COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689: IPR001543; KEGG: drt:Dret_0581 flagellar motor switch protein FliM; PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; SPTR: Flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
  
 
 0.911
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
  
 
 0.874
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.864
clpA
ATP-dependent Clp protease ATP-binding subunit ClpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR004176: IPR003959: IPR013093: IPR019489: IPR 001270: IPR018368: IPR003593: IPR013461; KEGG: dak:DaAHT2_2492 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease, ATP-binding subunit clpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino termi [...]
  
 
 0.864
ADW18650.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR003660: IPR000014: IPR001610: IPR 003661: IPR003594: IPR001789: IPR005467: IPR000700: IPR008207:I PR013655; KEGG: dba:Dbac_2628 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain contai [...]
  
 
 0.860
ADW19133.1
Multi-sensor hybrid histidine kinase; COGs: COG3614 periplasmic ligand-binding sensor domain; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 006189: IPR013767: IPR013656: IPR003594: IPR004358: IPR001610; KEGG: gsu:GSU2816 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; CHASE domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC sensor [...]
  
 
0.860
hslU
Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
  
  
 0.842
ADW18481.1
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR005467: IPR001789: IPR002545: IPR008207: IPR 003594: IPR004358; KEGG: nhl:Nhal_3349 response regulator receiver; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; CheW domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; CheW domain protein; SPTR: Sensor histidine kinase/response regulator; PFAM: CheW-like domain; Response regulator receiver domain; Histidin [...]
  
 
0.838
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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