STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17645.1Filamentation induced by cAMP protein Fic; COGs: COG3943 Virulence protein; InterPro IPR003812; KEGG: rrs:RoseRS_0280 death-on-curing protein; PFAM: filamentation induced by cAMP protein Fic; SPTR: Death-on-curing protein; PFAM: Fic/DOC family. (340 aa)    
Predicted Functional Partners:
ADW16445.1
Protein of unknown function DUF450; COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR014001: IPR007409: IPR006935; KEGG: dze:Dd1591_4250 protein of unknown function DUF450; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: Putative uncharacterized protein; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit.
  
    0.821
ADW17646.1
CRISPR-associated exonuclease, Cas4 family; COGs: COG1468 RecB family exonuclease; InterPro IPR013343; KEGG: sat:SYN_02474 exonuclease N; SPTR: RecB family exonuclease N; TIGRFAM: CRISPR-associated protein Cas4; PFAM: Domain of unknown function DUF83; TIGRFAM: CRISPR-associated protein Cas4.
       0.821
ADW17647.1
CRISPR-associated protein, Cas1 family; COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR019856: IPR002729; KEGG: sat:SYN_02473 putative cytoplasmic protein; PFAM: protein of unknown function DUF48; SPTR: Hypothetical cytosolic protein; TIGRFAM: CRISPR-associated protein Cas1; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1, DVULG subtype; CRISPR-associated endonuclease Cas1.
       0.821
ADW17648.1
CRISPR-associated protein, Cas2 family; COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR021127; KEGG: sat:SYN_02472 putative cytoplasmic protein; SPTR: Hypothetical cytosolic protein; TIGRFAM: CRISPR-associated protein Cas2; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2.
     
 0.820
ADW18759.1
COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); InterProIPR001679: IPR013840: IPR003583: IPR001357: IPR 018239: IPR013839: IPR004150: IPR004149: IPR000445; KEGG: dak:DaAHT2_2447 DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; NAD-dependent DNA ligase OB-fold; helix-hairpin-helix motif; BRCT domain protein; PRIAM: DNA ligase (NAD(+)); SMART: NAD-dependent DNA ligase; Helix-hairpin-helix DNA-binding class 1; BRCT domain protein; SPTR: DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase OB-fold domain; [...]
      0.737
ADW17644.1
CRISPR-associated protein, Csd2 family; COGs: COG3649 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR006482: IPR013418; KEGG: gme:Gmet_1067 CRISPR-associated Csh2 family protein; PFAM: CRISPR-associated protein TM1801; SPTR: CRISPR-associated protein TM1801; TIGRFAM: CRISPR-associated protein, Csd2 family; CRISPR-associated protein, CT1132 family; PFAM: Family of unknown function (DUF694); TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein, Csd2 family.
       0.706
ADW17641.1
CRISPR-associated helicase, Cas3 family; COGs: COG1203 helicase; InterProIPR006483: IPR006474: IPR014021: IPR011545: IPR 014001; KEGG: gme:Gmet_1064 metal dependent phosphohydrolase; PFAM: DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; SPTR: Metal dependent phosphohydrolase; TIGRFAM: CRISPR-associated HD domain protein; CRISPR-associated helicase Cas3; manually curated; PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD.
       0.653
ADW17642.1
CRISPR-associated protein, Csd5d family; InterPro IPR013422: IPR010155: IPR021124; KEGG: gme:Gmet_1065 CRISPR-associated Csd1 family protein; PFAM: CRISPR-associated protein, Cas5; SPTR: CRISPR-associated protein, CT1134; TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, Dvulg subtype; CRISPR-associated protein Cas5, N-terminal domain.
       0.640
ADW17643.1
InterPro IPR010144; KEGG: nhl:Nhal_1943 CRISPR-associated protein, Csd1 family; PFAM: CRISPR-associated protein CT1133; SPTR: CRISPR-associated protein, Csd1 family; TIGRFAM: CRISPR-associated protein, Csd1 family; PFAM: CRISPR-associated protein (Cas_Csd1); TIGRFAM: CRISPR-associated protein, Csd1 family.
       0.640
ADW16440.1
N-6 DNA methylase; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR002052: IPR002296: IPR003356; KEGG: dze:Dd1591_4253 N-6 DNA methylase; PFAM: N-6 DNA methylase; SPTR: N-6 DNA methylase; PFAM: N-6 DNA Methylase; HsdM N-terminal domain.
  
    0.575
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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