STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17704.1COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: dma:DMR_08520 alkaline phosphatase precursor; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase. (508 aa)    
Predicted Functional Partners:
ADW17703.1
YibE/F family protein; COGs: COG5438 multitransmembrane protein; InterPro IPR012507; KEGG: dsa:Desal_1743 YibE/F family protein; PFAM: YibE/F family protein; SPTR: YibE/F family protein; PFAM: YibE/F-like protein.
 
     0.914
ADW17526.1
preQ(0) biosynthesis protein QueD; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: dak:DaAHT2_0938 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
     
  0.900
ADW18029.1
Thiamine-phosphate diphosphorylase; COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: dba:Dbac_0929 thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase.
    
  0.900
ADW18076.1
Thiamine-phosphate diphosphorylase; COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: pth:PTH_0643 thiamine monophosphate synthase; PFAM: thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase.
    
  0.900
ADW18117.1
GTP cyclohydrolase I; COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: dak:DaAHT2_1707 protein of unknown function DUF198; PFAM: protein of unknown function DUF198; PRIAM: GTP cyclohydrolase I; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1469.
     
  0.900
ADW18191.1
COGs: COG0611 Thiamine monophosphate kinase; InterPro IPR006283: IPR000728: IPR010918; KEGG: dak:DaAHT2_1499 thiamine-monophosphate kinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; PRIAM: Thiamine-phosphate kinase; SPTR: Thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: thiamine-monophosphate kinase.
     
  0.900
ADW18963.1
GTP cyclohydrolase I; COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: dak:DaAHT2_0489 protein of unknown function DUF198; PFAM: protein of unknown function DUF198; PRIAM: GTP cyclohydrolase I; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1469.
     
  0.900
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
    
 
 0.885
ADW19288.1
Protein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
    
 
 0.881
ADW18183.1
Trigger factor; COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR005215: IPR008881: IPR001179: IPR008880; KEGG: dak:DaAHT2_1304 trigger factor; PFAM: trigger factor domain-containing protein; peptidylprolyl isomerase FKBP-type; SPTR: Trigger factor; TIGRFAM: trigger factor; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Bacterial trigger factor protein (TF); Bacterial trigger factor protein (TF) C-terminus; TIGRFAM: trigger factor.
    
 
 0.880
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (16%) [HD]