Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17708.1Alpha-2-macroglobulin domain protein; COGs: COG2373 Large extracellular alpha-helical protein; InterPro IPR002890: IPR011625; KEGG: pfs:PFLU6111 hypothetical protein; PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; SPTR: Putative uncharacterized protein; PFAM: Alpha-2-macroglobulin family; MG2 domain; Alpha-2-macroglobulin family N-terminal region; Alpha-2-macroglobulin MG1 domain. (1927 aa)    
Predicted Functional Partners:
ADW17707.1
Penicillin-binding protein 1C; COGs: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; InterPro IPR011815: IPR001264: IPR001460: IPR009647; KEGG: pfs:PFLU6112 putative penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; SPTR: Putative penicillin-binding protein; TIGRFAM: penicillin-binding protein 1C; PFAM: Penicillin-Binding Protein C-terminus Family; Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein 1C.
   
 0.982
ADW17580.1
KEGG: dol:Dole_1507 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.665
nrdR
ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
    
   0.546
ADW17392.1
COGs: COG2132 Putative multicopper oxidase; InterProIPR017909: IPR011707: IPR011706: IPR002355: IPR 006311; KEGG: dba:Dbac_0735 multicopper oxidase type 3; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Multicopper oxidase type 3; PFAM: Multicopper oxidase; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
  
 
 0.497
ADW17709.1
GCN5-related N-acetyltransferase; COGs: COG3153 acetyltransferase; InterPro IPR000182; KEGG: pca:Pcar_2865 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
       0.457
ADW16677.1
Von Willebrand factor type A; COGs: COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain; InterPro IPR002035; KEGG: cpi:Cpin_1196 von Willebrand factor type A; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: von Willebrand factor type A; PFAM: von Willebrand factor; von Willebrand factor type A domain; Domain of unknown function (DUF3520).
 
     0.413
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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