Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17716.1HNH endonuclease; InterPro IPR003615: IPR002711; KEGG: dps:DP2877 HNH endonuclease family protein; PFAM: HNH endonuclease; SMART: HNH nuclease; SPTR: Probable HNH endonuclease family protein; PFAM: HNH endonuclease. (103 aa)    
Predicted Functional Partners:
ADW17717.1
FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterProIPR001645: IPR013221: IPR004101: IPR018486: IPR 018109; KEGG: dak:DaAHT2_1269 FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase.
       0.814
ADW16289.1
COGs: COG3505 Type IV secretory pathway VirD4 protein; InterPro IPR000183; KEGG: sat:SYN_01886 DNA transfer in the process of conjugation and F pilus assembly protein; SPTR: DNA transfer in the process of conjugation and F pilus assembly protein; PFAM: Type IV secretion-system coupling protein DNA-binding domain.
   
 
 0.742
ADW17449.1
TRAG family protein; COGs: COG3505 Type IV secretory pathway VirD4 protein; InterPro IPR003688; KEGG: sat:SYN_01886 DNA transfer in the process of conjugation and F pilus assembly protein; PFAM: TRAG family protein; SPTR: DNA transfer in the process of conjugation and F pilus assembly protein; PFAM: Type IV secretion-system coupling protein DNA-binding domain.
   
 
 0.742
ADW17718.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212: IPR014016: IPR014017; KEGG: dps:DP2879 ATP-dependent DNA helicase UvrD; PFAM: UvrD/REP helicase; SPTR: Probable ATP-dependent DNA helicase, UvrD/REP family; PFAM: UvrD/REP helicase.
     
 0.673
ADW16679.1
COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR017926: IPR010073: IPR000728: IPR010918; KEGG: dps:DP0704 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Probable phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synt [...]
  
    0.478
ADW17715.1
COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042: IPR006043; KEGG: dvm:DvMF_0910 uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Uracil-xanthine permease; TIGRFAM: uracil-xanthine permease; PFAM: Permease family; TIGRFAM: uracil-xanthine permease.
       0.464
ADW17719.1
KEGG: dak:DaAHT2_1271 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.437
ADW17332.1
HRDC domain protein; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR002121; KEGG: dat:HRM2_02150 helicase-family protein; PFAM: HRDC domain protein; SMART: HRDC domain protein; SPTR: Helicase-family protein; PFAM: PIF1 helicase; HRDC domain.
     
 0.425
ADW17062.1
COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: dps:DP2618 hypothetical protein; PFAM: Iojap-related protein; SPTR: Putative uncharacterized protein; TIGRFAM: iojap-like protein; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein.
   
  
 0.401
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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