STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADW17724.1Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: gsu:GSU1643 GGDEF/response regulator receiver domain-containing protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: GGDEF/response regulator receiver domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (304 aa)    
Predicted Functional Partners:
ADW18447.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR001789: IPR002645: IPR001633: IPR000160; KEGG: app:CAP2UW1_1477 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; GGDEF domain containing protein; response regulator receiver; SMART: EAL domain protein; GGDEF domain containing protein; response regulator receiver; SPTR: Response regulator receiver modulated diguanylate cyclase/phosphodiesterase; TIGR [...]
  
 0.887
ADW16747.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014: IPR001633: IPR000160: IPR003660: IPR 013767: IPR001610; KEGG: dvm:DvMF_1530 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold domain protein; histidine kinase HAMP region domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Diguanylate cyclas [...]
 
 0.852
ADW17390.1
Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633: IPR000160: IPR000644; KEGG: pin:Ping_2411 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
 0.825
ADW18001.1
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674: IPR003607; KEGG: dps:DP1401 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Putative uncharacterized protein; PFAM: HD domain.
 
 
 0.807
ADW17377.1
Diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767; KEGG: pca:Pcar_2296 GGDEF domain-containing protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: FOG: GGDEF domain protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain.
  
 
   0.791
ADW16757.1
Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR000014: IPR013767: IPR006674: IPR003607; KEGG: dat:HRM2_20440 two component protein (transcriptional response regulator/sensory box); PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold domain protein; SMART: metal-dependent phosphohydrolase HD region; PAS domain containing protein; SPTR: Two component protein (Transcriptional response regulator/sensory box); TIGRFAM: PAS sensor protein; PFAM: HD domain; PAS fold; TIGRFAM: PAS domain S-box.
 
 0.767
ADW16756.1
Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR000014: IPR013767: IPR006674; KEGG: dat:HRM2_20440 two component protein (transcriptional response regulator/sensory box); PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold domain protein; SPTR: Two component protein (Transcriptional response regulator/sensory box); TIGRFAM: PAS sensor protein; PFAM: HD domain; PAS fold; TIGRFAM: PAS domain S-box.
 
 0.757
ADW19430.1
Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789: IPR006674: IPR006675: IPR003607; KEGG: dps:DP0645 Ntr family protein two-component system response regulator; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; SPTR: Related to two-component system response regulator (Ntr family); TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; Res [...]
 
    0.752
ADW17723.1
Protein of unknown function DUF328; COGs: COG3022 conserved hypothetical protein; InterPro IPR005583; KEGG: rcu:RCOM_0102930 hypothetical protein; PFAM: protein of unknown function DUF328; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF328).
       0.727
ADW17262.1
Response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor; COGs: COG2199 FOG: GGDEF domain; InterProIPR001789: IPR000014: IPR000700: IPR000160: IPR 001610: IPR013767; KEGG: mpt:Mpe_A2857 sensory box/response regulator; PFAM: GGDEF domain containing protein; response regulator receiver; PAS fold domain protein; SMART: GGDEF domain containing protein; response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; SPTR: Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: diguanylate cy [...]
 
0.724
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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