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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17739.1COGs: COG0061 sugar kinase; InterPro IPR002504; KEGG: dak:DaAHT2_1073 NAD(+) kinase; PFAM: ATP-NAD/AcoX kinase; SPTR: NAD(+) kinase; PFAM: ATP-NAD kinase. (287 aa)    
Predicted Functional Partners:
ADW17034.1
NH(3)-dependent NAD(+) synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010: IPR003694: IPR014445; KEGG: dps:DP2919 glutamine-dependent NAD(+) synthetase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Probable glutamine-dependent NAD(+) synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; Carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase.
    
 0.947
ADW17259.1
COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; InterPro IPR004820: IPR005248: IPR004821; KEGG: dak:DaAHT2_1154 nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Nicotinate (Nicotinamide) nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain.
  
 
 0.938
ADW18107.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: acp:A2cp1_4171 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Silent information regulator protein Sir2; PFAM: Sir2 family.
  
 
 0.918
ADW19327.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: dak:DaAHT2_0111 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Silent information regulator protein Sir2; PFAM: Sir2 family.
  
 
 0.918
ADW17738.1
COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR000304: IPR004455; KEGG: gme:Gmet_0899 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase.
     
 0.833
ADW16845.1
Sigma 54 interacting domain protein; COGs: COG0497 ATPase involved in DNA repair; InterPro IPR003395: IPR004604: IPR002078; KEGG: dak:DaAHT2_0696 DNA repair protein RecN; PFAM: SMC domain protein; SPTR: DNA repair protein RecN; TIGRFAM: DNA repair protein RecN; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN.
 
  
 0.767
ADW18327.1
COGs: COG1189 rRNA methylase; InterPro IPR002942: IPR002877: IPR004538; KEGG: dak:DaAHT2_0442 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: Hemolysin A; TIGRFAM: hemolysin A; manually curated; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein.
  
  
 0.618
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...]
 
    0.545
ADW18843.1
COGs: COG0686 Alanine dehydrogenase; InterPro IPR008141: IPR008143: IPR007886: IPR007698; KEGG: gbm:Gbem_1176 alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; PRIAM: Alanine dehydrogenase; SPTR: Alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase.
    
  0.545
ADW17704.1
COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: dma:DMR_08520 alkaline phosphatase precursor; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase.
   
 
  0.508
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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