STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17740.1ATP-dependent helicase HrpB; COGs: COG1643 HrpA-like helicase; InterProIPR010225: IPR014001: IPR001650: IPR011545: IPR 007502: IPR013689: IPR014021; KEGG: dak:DaAHT2_0986 ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase-associated domain protein; helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; ATP-dependent helicase C-terminal; Helicase associated domain (HA2); DEAD/DEAH [...] (842 aa)    
Predicted Functional Partners:
ADW17100.1
Peptidylprolyl isomerase; COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130: IPR001179: IPR020892; KEGG: dps:DP1645 peptidyl-prolyl cis-trans isomerase; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; peptidylprolyl isomerase FKBP-type; PRIAM: Peptidylprolyl isomerase; SPTR: Probable peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD.
  
 0.949
rpsE
SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
   
  0.848
ADW16986.1
COGs: COG0522 Ribosomal protein S4 and related protein; InterPro IPR001912: IPR002942: IPR005709: IPR018079; KEGG: dps:DP1151 30S ribosomal protein S4; PFAM: ribosomal protein S4; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: 30S ribosomal protein S4; TIGRFAM: ribosomal protein S4; PFAM: Ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type.
   
  0.846
rpsK
SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
  0.831
rpsO
SSU ribosomal protein S15P; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
    
  0.827
ADW16976.1
COGs: COG0096 Ribosomal protein S8; InterPro IPR000630; KEGG: lga:LGAS_0304 30S ribosomal protein S8; PFAM: ribosomal protein S8; SPTR: Ribosomal protein S8; manually curated; PFAM: Ribosomal protein S8.
    
  0.813
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
  0.810
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
    
  0.809
ADW16966.1
COGs: COG0088 Ribosomal protein L4; InterPro IPR002136; KEGG: dak:DaAHT2_1451 ribosomal protein L4/L1e; PFAM: ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4; PFAM: Ribosomal protein L4/L1 family.
    
  0.805
ADW16334.1
KEGG: maq:Maqu_0130 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 0.766
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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