Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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ADW17755.1Iron-only hydrogenase maturation protein HydF; COGs: COG1160 GTPase; InterPro IPR005225: IPR002917; KEGG: sfu:Sfum_1843 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain. (416 aa)    
Predicted Functional Partners:
ADW17756.1
Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterPro IPR006638: IPR007197: IPR005244; KEGG: sfu:Sfum_1844 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthase; PFAM: Radical SAM superfamily.
   
 0.991
ADW17757.1
Fe-S cluster domain protein; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR007202: IPR017896: IPR017900; KEGG: sfu:Sfum_1846 putative PAS/PAC sensor protein; PFAM: Fe-S cluster domain protein; SPTR: Putative PAS/PAC sensor protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Putative Fe-S cluster.
 
     0.947
ADW17758.1
InterPro IPR001932: IPR010822; KEGG: sfu:Sfum_1847 stage II sporulation E family protein; PFAM: Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: Stage II sporulation E family protein; PFAM: Stage II sporulation protein E (SpoIIE).
 
     0.913
ADW18047.1
Iron-only hydrogenase maturation protein HydG; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197: IPR010722; KEGG: cbi:CLJ_B3912 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SPTR: Putative thiazole biosynthesis protein; PFAM: Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH.
   
 0.901
ADW17753.1
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352: IPR001041: IPR019574: IPR004108: IPR 003149: IPR017896: IPR017900: IPR000283; KEGG: dma:DMR_07830 putative Fe hydrogenase; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Putative Fe hydrogenase; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulf [...]
 
   
 0.890
ADW19068.1
COGs: COG0358 DNA primase; InterProIPR002694: IPR013264: IPR006171: IPR019475: IPR 006154: IPR006295; KEGG: dak:DaAHT2_2321 DNA primase; PFAM: DNA primase catalytic core domain; TOPRIM domain-containing protein; DNA primase, DnaB-helicase binding domain; SMART: Toprim sub domain-containing protein; SPTR: DNA primase; TIGRFAM: DNA primase; PFAM: Toprim domain; DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; DnaB-helicase binding domain of primase; TIGRFAM: DNA primase, catalytic core.
   
  
 0.862
ADW17754.1
Fumarate lyase; COGs: COG1027 Aspartate ammonia-lyase; InterPro IPR000362: IPR018951: IPR020557: IPR018201; KEGG: sfu:Sfum_1842 aspartate ammonia-lyase; PFAM: fumarate lyase; Fumarase C-like; SPTR: Fumarate lyase; PFAM: Lyase; Fumarase C C-terminus.
 
  
 0.842
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
 
 0.828
ADW19420.1
COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR011128: IPR006109: IPR006168; KEGG: dps:DP0651 glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus.
  
  
 0.819
rplN
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
 
 0.815
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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