STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17756.1Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterPro IPR006638: IPR007197: IPR005244; KEGG: sfu:Sfum_1844 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthase; PFAM: Radical SAM superfamily. (439 aa)    
Predicted Functional Partners:
ADW17755.1
Iron-only hydrogenase maturation protein HydF; COGs: COG1160 GTPase; InterPro IPR005225: IPR002917; KEGG: sfu:Sfum_1843 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.
   
 0.991
ADW16201.1
COGs: COG0132 Dethiobiotin synthetase; InterPro IPR004472; KEGG: cpb:Cphamn1_2454 dethiobiotin synthase; SPTR: Dethiobiotin synthetase; TIGRFAM: dethiobiotin synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: dethiobiotin synthase.
  
 
 0.986
ADW17757.1
Fe-S cluster domain protein; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR007202: IPR017896: IPR017900; KEGG: sfu:Sfum_1846 putative PAS/PAC sensor protein; PFAM: Fe-S cluster domain protein; SPTR: Putative PAS/PAC sensor protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Putative Fe-S cluster.
 
  
 0.954
ADW19076.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
  
 
 0.947
ADW17753.1
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352: IPR001041: IPR019574: IPR004108: IPR 003149: IPR017896: IPR017900: IPR000283; KEGG: dma:DMR_07830 putative Fe hydrogenase; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Putative Fe hydrogenase; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulf [...]
 
  
 0.924
ADW16462.1
COGs: COG0502 Biotin synthase; InterPro IPR006638: IPR002684: IPR007197: IPR010722; KEGG: cpu:cpfrc_00908 biotin synthetase; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; PRIAM: Biotin synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Biotin synthase 2; TIGRFAM: biotin synthase; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: biotin synthetase.
  
  
  0.914
ADW17758.1
InterPro IPR001932: IPR010822; KEGG: sfu:Sfum_1847 stage II sporulation E family protein; PFAM: Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: Stage II sporulation E family protein; PFAM: Stage II sporulation protein E (SpoIIE).
 
    0.905
ADW16463.1
COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005814: IPR005815; KEGG: see:SNSL254_A0857 adenosylmethionine--8-amino-7-oxononanoate transaminase; PFAM: aminotransferase class-III; SPTR: Adenosylmethionine-8-amino-7-oxononanoate transaminase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase.
  
  
 0.863
ADW16786.1
8-amino-7-oxononanoate synthase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004723: IPR004839: IPR001917; KEGG: pph:Ppha_2838 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; PRIAM: 8-amino-7-oxononanoate synthase; SPTR: 8-amino-7-oxononanoate synthase; TIGRFAM: 8-amino-7-oxononanoate synthase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase.
  
  
 0.855
ADW17754.1
Fumarate lyase; COGs: COG1027 Aspartate ammonia-lyase; InterPro IPR000362: IPR018951: IPR020557: IPR018201; KEGG: sfu:Sfum_1842 aspartate ammonia-lyase; PFAM: fumarate lyase; Fumarase C-like; SPTR: Fumarate lyase; PFAM: Lyase; Fumarase C C-terminus.
 
 
   0.835
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (32%) [HD]