Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17763.1COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; InterProIPR005259: IPR014001: IPR001650: IPR011545: IPR 014021; KEGG: dak:DaAHT2_0366 primosomal protein N'; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Primosomal protein n; TIGRFAM: primosomal protein N'; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: primosomal protein N'. (767 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.835
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.834
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 
 0.832
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
   
 
 0.825
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.810
galU
COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005771: IPR005835; KEGG: dak:DaAHT2_0367 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; SPTR: UTP--glucose-1-phosphate uridylyltransferase, bacterial and archaeal type; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase.
       0.722
ADW17929.1
single-stranded-DNA-specific exonuclease RecJ; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR004610: IPR001667: IPR003156; KEGG: mxa:MXAN_4688 single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: DHH family; DHHA1 domain; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ.
 
   
 0.711
ADW17080.1
COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); InterProIPR003594: IPR013507: IPR014790: IPR020667: IPR 014763; KEGG: dak:DaAHT2_1338 DNA mismatch repair protein MutL; PFAM: MutL dimerisation; DNA mismatch repair protein domain protein; ATP-binding region ATPase domain protein; SPTR: DNA mismatch repair protein MutL; TIGRFAM: DNA mismatch repair protein MutL; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; MutL C terminal dimerisation domain; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL.
  
  
 0.703
ADW18619.1
COGs: COG0193 Peptidyl-tRNA hydrolase; InterPro IPR001328: IPR018171; KEGG: bha:BH0068 peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase.
  
  
 0.667
ADW16871.1
UDP-N-acetylenolpyruvoylglucosamine reductase; COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; InterPro IPR006094: IPR011601: IPR003170: IPR016166; KEGG: dak:DaAHT2_1479 UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain-containing protein; FAD linked oxidase domain protein; PRIAM: UDP-N-acetylmuramate dehydrogenase; SPTR: UDP-N-acetylenolpyruvoylglucosamine reductase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N- [...]
 
   
 0.656
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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