Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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ADW17765.1COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014: IPR003661: IPR003594: IPR013767: IPR 004358: IPR005467; KEGG: dak:DaAHT2_0611 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: Histidin [...] (619 aa)    
Predicted Functional Partners:
ADW17094.1
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789: IPR002078: IPR002197: IPR020441: IPR 003593; KEGG: dak:DaAHT2_0539 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response [...]
 
  0.952
ADW16876.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterPro IPR003661: IPR003594: IPR004358: IPR005467; KEGG: dak:DaAHT2_1474 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: ATP-binding region, ATPase-like:Histidine kinase A-like; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
 
0.934
ADW16798.1
PAS modulated sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR001789: IPR013656: IPR002078: IPR002197: IPR 020441: IPR000014: IPR003593; KEGG: gsu:GSU2506 sensory box protein/sigma-54 dependent DNA-binding response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; PAS fold-4 domain protein; helix-turn-helix Fis-type; SMART: response regulator receiver; PAS domain containing protein; AAA ATPase; SPTR: Sensory box protein/si [...]
 
 
 0.928
ADW17207.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR005467: IPR003661: IPR003594; KEGG: sat:SYN_01094 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
 
 
0.927
ADW18989.1
Sigma 54 interacting domain protein; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078: IPR003660: IPR003593; KEGG: dvu:DVU0151 HAMP domain/sigma-54 interaction domain-containing protein; PFAM: sigma-54 factor interaction domain-containing protein; histidine kinase HAMP region domain protein; SMART: AAA ATPase; SPTR: HAMP domain/sigma-54 interaction domain protein; PFAM: Sigma-54 interaction domain.
    
  0.904
ADW17006.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dal:Dalk_1498 histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Histidine kinase; PFAM: Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
 
 
 
 0.796
ADW18483.1
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: ttu:TERTU_0232 response regulator receiver domain protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
  
 
 
 0.776
ADW16671.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: tye:THEYE_A0734 FrgC; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: FrgC; PFAM: Response regulator receiver domain.
 
   0.758
ADW17323.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: tye:THEYE_A0734 FrgC; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: FrgC; PFAM: Response regulator receiver domain.
 
   0.758
ADW17974.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dal:Dalk_3180 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
   0.758
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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