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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17820.1Aminotransferase class I and II; COGs: COG3977 Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase; InterPro IPR004839; KEGG: hch:HCH_01903 valine--pyruvate transaminase; PFAM: aminotransferase class I and II; SPTR: Alanine-alpha-ketoisovalerate/valine-pyruvate aminotransferase; PFAM: Aminotransferase class I and II. (419 aa)    
Predicted Functional Partners:
ADW18827.1
COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005786: IPR018300: IPR001544; KEGG: dps:DP0192 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain-amino-acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II.
     
 0.918
ilvD
COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR020558: IPR004404: IPR000581; KEGG: pdi:BDI_2073 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
     
 0.913
ADW17096.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176: IPR004839; KEGG: dak:DaAHT2_1654 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
     
0.904
ADW17926.1
(R)-citramalate synthase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterProIPR005675: IPR000891: IPR013709: IPR001917: IPR 002034; KEGG: dps:DP0660 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: LeuA allosteric (dimerisation) domain-containing protein; pyruvate carboxyltransferase; SPTR: Probable 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to [...]
     
 0.901
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
     
 0.901
ADW17817.1
Binding-protein-dependent transport systems inner membrane component; COGs: COG4239 ABC-type uncharacterized transport system permease component; InterPro IPR000515; KEGG: lhk:LHK_01099 DppC2; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
 
     0.557
ADW17818.1
Binding-protein-dependent transport systems inner membrane component; COGs: COG4174 ABC-type uncharacterized transport system permease component; InterPro IPR000515; KEGG: pnu:Pnuc_1236 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
 
     0.536
ADW18093.1
COGs: COG0787 Alanine racemase; InterPro IPR000821: IPR020622: IPR001608: IPR011079; KEGG: dak:DaAHT2_1666 alanine racemase; PFAM: alanine racemase domain protein; PRIAM: Alanine racemase; SPTR: Alanine racemase; TIGRFAM: alanine racemase; PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase.
     
 0.521
ADW17819.1
Hypothetical protein; KEGG: tgu:100220328 similar to RIKEN cDNA A930021H16; SPTR: Putative uncharacterized protein.
       0.520
ADW19407.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: dps:DP0725 DNA-binding transcriptional regulator IlvY; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: Probable transcriptional activator protein (IlvY); PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain.
  
     0.496
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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