Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW17826.1Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: dps:DP2742 cardiolipin synthetase; PFAM: phospholipase D/Transphosphatidylase; SMART: phospholipase D/Transphosphatidylase; SPTR: Related to cardiolipin synthetase; PFAM: Phospholipase D Active site motif. (487 aa)    
Predicted Functional Partners:
ADW16735.1
Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: gsu:GSU0482 cardiolipin synthetase, putative; PFAM: phospholipase D/Transphosphatidylase; SMART: phospholipase D/Transphosphatidylase; SPTR: Cardiolipin synthetase, putative; PFAM: Phospholipase D Active site motif.
  
  
 
0.921
ADW19381.1
COGs: COG1267 Phosphatidylglycerophosphatase A and related protein; InterPro IPR007686; KEGG: dps:DP0749 phosphatidylglycerophosphatase A; PFAM: phosphatidylglycerophosphatase A; SPTR: Related to phosphatidylglycerophosphatase A; PFAM: Phosphatidylglycerophosphatase A.
     
 0.913
ADW17827.1
Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979: IPR004843: IPR011152; KEGG: mhu:Mhun_2988 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family.
       0.660
ADW18923.1
COGs: COG0194 Guanylate kinase; InterPro IPR008144: IPR017665: IPR020590: IPR008145; KEGG: dak:DaAHT2_0280 guanylate kinase; PFAM: guanylate kinase; PRIAM: Guanylate kinase; SMART: guanylate kinase/L-type calcium channel region; SPTR: Guanylate kinase; TIGRFAM: guanylate kinase; PFAM: Guanylate kinase; TIGRFAM: guanylate kinase.
   
 0.518
ADW16708.1
CDP-diacylglycerol/glycerol-3-phosphate3-phospha tidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR004570: IPR000462; KEGG: dps:DP0426 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: Probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.
 
   
 0.511
ADW17171.1
Hypothetical protein; InterPro IPR000719; KEGG: dsa:Desal_2316 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 0.508
ADW18853.1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; InterPro IPR003526: IPR001228: IPR018294: IPR020555; KEGG: dps:DP0257 bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; PFAM: MECDP-synthase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: Bifunctional enzyme ispD/ispF; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: YgbB family; Uncharacterized pr [...]
     
 0.507
ADW18906.1
Endonuclease/exonuclease/phosphatase; COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: dol:Dole_2329 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/Exonuclease/phosphatase family.
 
    0.497
ADW17822.1
COGs: COG2062 Phosphohistidine phosphatase SixA; InterPro IPR013078; KEGG: mca:MCA3096 phosphoglycerate mutase domain-containing protein; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase family domain protein; PFAM: Phosphoglycerate mutase family.
       0.491
ADW16334.1
KEGG: maq:Maqu_0130 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 0.487
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (10%) [HD]