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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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ADW17857.1COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR002125: IPR016192; KEGG: dak:DaAHT2_0309 CMP/dCMP deaminase zinc-binding protein; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: CMP/dCMP deaminase zinc-binding protein; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. (146 aa)    
Predicted Functional Partners:
ADW17204.1
tRNA(Ile)-lysidine synthetase; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063: IPR012795; KEGG: dps:DP2932 cell cycle protein MesJ; PFAM: PP-loop domain protein; SPTR: tRNA(Ile)-lysidine synthase; TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop family; TIGRFAM: tRNA(Ile)-lysidine synthetase, N-terminal domain.
 
  
 0.920
ADW19076.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
  
    0.869
ADW18796.1
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000639: IPR000073; KEGG: dps:DP2632 haloalkane dehalogenase; PFAM: alpha/beta hydrolase fold; SPTR: Related to haloalkane dehalogenase; PFAM: alpha/beta hydrolase fold.
      0.822
ADW18061.1
methylmalonyl-CoA epimerase; InterPro IPR017515: IPR004360; KEGG: dat:HRM2_32480 glyoxalase/dioxygenase/bleomycin resistance family protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/dioxygenase/bleomycin resistance family protein; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase.
   
  
 0.587
ADW17858.1
UspA domain-containing protein; InterPro IPR006016; KEGG: sfu:Sfum_2271 UspA domain-containing protein; PFAM: UspA domain-containing protein; SPTR: UspA domain protein; PFAM: Universal stress protein family.
       0.572
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
  
 0.541
ADW19136.1
COGs: COG0313 methyltransferase; InterPro IPR000878: IPR018063: IPR008189; KEGG: dps:DP1634 hypothetical protein; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Putative uncharacterized protein; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: probable S-adenosylmethionine-dependent methyltransferase, YraL family.
 
    0.523
ADW18775.1
Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterProIPR003265: IPR000097: IPR004808: IPR020847: IPR 020848: IPR004036: IPR003651: IPR005135; KEGG: dak:DaAHT2_1503 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; HhH-GPD family protein; iron-sulfur cluster loop; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD family protein; SPTR: Exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; HhH-GPD superfamily base excision DNA repair protein; H [...]
    
 0.492
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
     
 0.482
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.481
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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