Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW17859.1Potassium/proton antiporter, CPA1 family; COGs: COG3263 NhaP-type Na+/H+ and K+/H+ antiporter with a unique C-terminal domain; InterPro IPR006153: IPR006037; KEGG: rba:RB11069 potassium/proton antiporter; PFAM: sodium/hydrogen exchanger; TrkA-C domain protein; SPTR: NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain; PFAM: TrkA-C domain; Sodium/hydrogen exchanger family; TC 2.A.36. (580 aa)    
Predicted Functional Partners:
ADW17858.1
UspA domain-containing protein; InterPro IPR006016; KEGG: sfu:Sfum_2271 UspA domain-containing protein; PFAM: UspA domain-containing protein; SPTR: UspA domain protein; PFAM: Universal stress protein family.
       0.603
ADW17860.1
Sigma54 specific transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR003593: IPR002078: IPR002197: IPR020441; KEGG: sfu:Sfum_0948 two component, sigma54 specific, fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain.
       0.527
ADW17864.1
Kef-type potassium/proton antiporter, CPA2 family; COGs: COG4651 Kef-type K+ transport system predicted NAD-binding component; InterPro IPR006153: IPR003148: IPR006037; KEGG: dps:DP1776 potassium efflux transporter; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; SPTR: Related to potassium efflux transporter; PFAM: TrkA-N domain; TrkA-C domain; Sodium/hydrogen exchanger family; TIGRFAM: transporter, monovalent cation:proton antiporter-2 (CPA2) family; TC 2.A.37.1.
     
 0.509
ADW17857.1
COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR002125: IPR016192; KEGG: dak:DaAHT2_0309 CMP/dCMP deaminase zinc-binding protein; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: CMP/dCMP deaminase zinc-binding protein; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region.
       0.455
ADW18248.1
Multisubunit potassium/proton antiporter, PhaA subunit; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR003916: IPR001516: IPR001750: IPR007182; KEGG: dba:Dbac_2484 putative monovalent cation/H+ antiporter subunit A; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; Na+/H+ antiporter MnhB subunit-related protein; SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; NADH-Ubiquinone/plastoquinone [...]
      
 0.455
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (16%) [HD]