| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADW17861.1 | ADW17862.1 | Despr_1709 | Despr_1710 | COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR014864; KEGG: dak:DaAHT2_2678 transcriptional regulator NikR, CopG family; PFAM: NikR nickel binding; SPTR: Transcriptional regulator NikR, CopG family; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain; TIGRFAM: nickel-responsive transcriptional regulator NikR. | Peptidase M48 Ste24p; COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR019734: IPR001915: IPR013026; KEGG: dps:DP2629 hypothetical protein; PFAM: peptidase M48 Ste24p; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M48. | 0.773 |
| ADW17861.1 | ADW17863.1 | Despr_1709 | Despr_1711 | COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR014864; KEGG: dak:DaAHT2_2678 transcriptional regulator NikR, CopG family; PFAM: NikR nickel binding; SPTR: Transcriptional regulator NikR, CopG family; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain; TIGRFAM: nickel-responsive transcriptional regulator NikR. | FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR006094: IPR004113: IPR004017: IPR017896: IPR 016166: IPR017900; KEGG: afw:Anae109_2999 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: FAD linked oxidase domain protein; PFAM: Cysteine-rich domain; FAD binding domain; Protein of unknown function (DUF3683); FAD linked oxidases, C-terminal domain. | 0.503 |
| ADW17861.1 | ADW17900.1 | Despr_1709 | Despr_1750 | COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR014864; KEGG: dak:DaAHT2_2678 transcriptional regulator NikR, CopG family; PFAM: NikR nickel binding; SPTR: Transcriptional regulator NikR, CopG family; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain; TIGRFAM: nickel-responsive transcriptional regulator NikR. | COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); InterPro IPR000688; KEGG: dps:DP0582 hydrogenase accessory protein HypA; PFAM: hydrogenase expression/synthesis HypA; SPTR: Probable hydrogenase accessory protein HypA; PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA. | 0.423 |
| ADW17861.1 | ADW17901.1 | Despr_1709 | Despr_1751 | COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR014864; KEGG: dak:DaAHT2_2678 transcriptional regulator NikR, CopG family; PFAM: NikR nickel binding; SPTR: Transcriptional regulator NikR, CopG family; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain; TIGRFAM: nickel-responsive transcriptional regulator NikR. | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR003495: IPR012202; KEGG: dps:DP0583 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Probable hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | 0.405 |
| ADW17861.1 | ADW19076.1 | Despr_1709 | Despr_2943 | COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR014864; KEGG: dak:DaAHT2_2678 transcriptional regulator NikR, CopG family; PFAM: NikR nickel binding; SPTR: Transcriptional regulator NikR, CopG family; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain; TIGRFAM: nickel-responsive transcriptional regulator NikR. | COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region. | 0.449 |
| ADW17862.1 | ADW17861.1 | Despr_1710 | Despr_1709 | Peptidase M48 Ste24p; COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR019734: IPR001915: IPR013026; KEGG: dps:DP2629 hypothetical protein; PFAM: peptidase M48 Ste24p; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M48. | COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR014864; KEGG: dak:DaAHT2_2678 transcriptional regulator NikR, CopG family; PFAM: NikR nickel binding; SPTR: Transcriptional regulator NikR, CopG family; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain; TIGRFAM: nickel-responsive transcriptional regulator NikR. | 0.773 |
| ADW17862.1 | ADW17863.1 | Despr_1710 | Despr_1711 | Peptidase M48 Ste24p; COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR019734: IPR001915: IPR013026; KEGG: dps:DP2629 hypothetical protein; PFAM: peptidase M48 Ste24p; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M48. | FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR006094: IPR004113: IPR004017: IPR017896: IPR 016166: IPR017900; KEGG: afw:Anae109_2999 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: FAD linked oxidase domain protein; PFAM: Cysteine-rich domain; FAD binding domain; Protein of unknown function (DUF3683); FAD linked oxidases, C-terminal domain. | 0.461 |
| ADW17863.1 | ADW17861.1 | Despr_1711 | Despr_1709 | FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR006094: IPR004113: IPR004017: IPR017896: IPR 016166: IPR017900; KEGG: afw:Anae109_2999 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: FAD linked oxidase domain protein; PFAM: Cysteine-rich domain; FAD binding domain; Protein of unknown function (DUF3683); FAD linked oxidases, C-terminal domain. | COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR014864; KEGG: dak:DaAHT2_2678 transcriptional regulator NikR, CopG family; PFAM: NikR nickel binding; SPTR: Transcriptional regulator NikR, CopG family; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain; TIGRFAM: nickel-responsive transcriptional regulator NikR. | 0.503 |
| ADW17863.1 | ADW17862.1 | Despr_1711 | Despr_1710 | FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR006094: IPR004113: IPR004017: IPR017896: IPR 016166: IPR017900; KEGG: afw:Anae109_2999 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: FAD linked oxidase domain protein; PFAM: Cysteine-rich domain; FAD binding domain; Protein of unknown function (DUF3683); FAD linked oxidases, C-terminal domain. | Peptidase M48 Ste24p; COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR019734: IPR001915: IPR013026; KEGG: dps:DP2629 hypothetical protein; PFAM: peptidase M48 Ste24p; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M48. | 0.461 |
| ADW17900.1 | ADW17861.1 | Despr_1750 | Despr_1709 | COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); InterPro IPR000688; KEGG: dps:DP0582 hydrogenase accessory protein HypA; PFAM: hydrogenase expression/synthesis HypA; SPTR: Probable hydrogenase accessory protein HypA; PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA. | COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR014864; KEGG: dak:DaAHT2_2678 transcriptional regulator NikR, CopG family; PFAM: NikR nickel binding; SPTR: Transcriptional regulator NikR, CopG family; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain; TIGRFAM: nickel-responsive transcriptional regulator NikR. | 0.423 |
| ADW17900.1 | ADW17901.1 | Despr_1750 | Despr_1751 | COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); InterPro IPR000688; KEGG: dps:DP0582 hydrogenase accessory protein HypA; PFAM: hydrogenase expression/synthesis HypA; SPTR: Probable hydrogenase accessory protein HypA; PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA. | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR003495: IPR012202; KEGG: dps:DP0583 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Probable hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | 0.995 |
| ADW17901.1 | ADW17861.1 | Despr_1751 | Despr_1709 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR003495: IPR012202; KEGG: dps:DP0583 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Probable hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR014864; KEGG: dak:DaAHT2_2678 transcriptional regulator NikR, CopG family; PFAM: NikR nickel binding; SPTR: Transcriptional regulator NikR, CopG family; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain; TIGRFAM: nickel-responsive transcriptional regulator NikR. | 0.405 |
| ADW17901.1 | ADW17900.1 | Despr_1751 | Despr_1750 | Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR003495: IPR012202; KEGG: dps:DP0583 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Probable hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); InterPro IPR000688; KEGG: dps:DP0582 hydrogenase accessory protein HypA; PFAM: hydrogenase expression/synthesis HypA; SPTR: Probable hydrogenase accessory protein HypA; PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA. | 0.995 |
| ADW19076.1 | ADW17861.1 | Despr_2943 | Despr_1709 | COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region. | COGs: COG0864 transcriptional regulator protein containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain; InterPro IPR014864; KEGG: dak:DaAHT2_2678 transcriptional regulator NikR, CopG family; PFAM: NikR nickel binding; SPTR: Transcriptional regulator NikR, CopG family; PFAM: Ribbon-helix-helix protein, copG family; NikR C terminal nickel binding domain; TIGRFAM: nickel-responsive transcriptional regulator NikR. | 0.449 |