Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17886.1PAS sensor protein; InterPro IPR000014: IPR000792: IPR013656; KEGG: dat:HRM2_48450 putative regulatory protein; PFAM: regulatory protein LuxR; PAS fold-4 domain protein; SMART: regulatory protein LuxR; SPTR: Putative regulatory protein; TIGRFAM: PAS sensor protein; manually curated; PFAM: Bacterial regulatory proteins, luxR family; PAS fold; TIGRFAM: PAS domain S-box. (284 aa)    
Predicted Functional Partners:
ADW17887.1
Protein of unknown function DUF190; InterPro IPR003793; KEGG: rfr:Rfer_1947 hypothetical protein; PFAM: protein of unknown function DUF190; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1993.
       0.689
ADW17888.1
Camphor resistance protein CrcB; COGs: COG0239 Integral membrane protein possibly involved in chromosome condensation; InterPro IPR003691; KEGG: tau:Tola_2564 CrcB protein; PFAM: Camphor resistance CrcB protein; SPTR: Protein crcB homolog; TIGRFAM: CrcB protein; PFAM: CrcB-like protein; TIGRFAM: crcB protein.
       0.641
ADW17261.1
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR008207: IPR 003661: IPR003594; KEGG: pth:PTH_2386 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SPTR: Signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [...]
 
    
 0.620
ADW18942.1
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR003661: IPR003594: IPR 004358; KEGG: dal:Dalk_3918 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Multi-sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
 
    
 0.571
ADW17277.1
Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: dak:DaAHT2_0193 rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.
  
 
 
 0.497
ADW17116.1
Hypothetical protein; COGs: COG0305 Replicative DNA helicase; InterPro IPR007694; KEGG: ade:Adeh_1793 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: DnaB-like helicase C terminal domain.
  
     0.470
ADW16838.1
KEGG: dat:HRM2_11340 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: General secretion pathway, M protein.
  
   
 0.465
ADW19026.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR003660: IPR003661: IPR 003594: IPR004358; KEGG: gbm:Gbem_3181 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SPTR: Hpt sensor hybrid histidine kinase; [...]
 
    
 0.456
ADW17791.1
Cytidylate kinase, Cmk2; COGs: COG1102 Cytidylate kinase; KEGG: dat:HRM2_39230 Cmk2; SPTR: Cmk2.
  
     0.443
ADW17907.1
Protein of unknown function DUF2284, metal-binding protein; COGs: COG5423 metal-binding protein; InterPro IPR019271; KEGG: ppd:Ppro_0853 metal-binding protein-like protein; PFAM: Protein of unknown function DUF2284, metal-binding; SPTR: Metal-binding protein-like protein; PFAM: Predicted metal-binding protein (DUF2284).
  
     0.443
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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