close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17890.1Regulatory protein MerR; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR000551: IPR004017: IPR017896: IPR017900; KEGG: dps:DP1009 Fe-S oxidoreductase; PFAM: regulatory protein MerR; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Probable Fe-S oxidoreductase; PFAM: Cysteine-rich domain. (492 aa)    
Predicted Functional Partners:
ADW17891.1
Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR003953: IPR013027: IPR000103: IPR017896: IPR 017900; KEGG: dps:DP1010 heterodisulfide reductase, subunit A; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Related to heterodisulfide reductase, subunit A; PFAM: Pyridine nucleotide-disulphide oxidoreductase; FAD binding domain; 4Fe-4S binding domain.
 
     0.891
ADW16564.1
Protein of unknown function DUF162; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR017896: IPR003741: IPR004017: IPR017900; KEGG: gur:Gura_0152 hypothetical protein; PFAM: protein of unknown function DUF162; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain; Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein.
 
 
0.858
ADW17889.1
COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: dps:DP1008 coenzyme F420 hydrogenase, delta subunit; PFAM: peptidase M52 hydrogen uptake protein; SPTR: Related to coenzyme F420 hydrogenase, delta subunit; TIGRFAM: hydrogenase maturation protease; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease.
 
   
 0.848
ADW17892.1
COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: dps:DP1011 methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: Methyl-viologen-reducing hydrogenase, delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
 
   
 0.822
ADW17893.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG1941 Coenzyme F420-reducing hydrogenase gamma subunit; InterPro IPR006137: IPR018486; KEGG: dps:DP1012 methyl viologen-reducing hydrogenase, gamma chain; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: Related to methyl viologen-reducing hydrogenase, gamma chain; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
   
 0.820
dsrA
COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterPro IPR017896: IPR006067: IPR011806; KEGG: dps:DP0797 dissimilatory sulfite reductase, alpha subunit (DsrA); PFAM: nitrite and sulphite reductase 4Fe-4S region; PRIAM: Hydrogensulfite reductase; SPTR: Dissimilatory sulfite reductase subunit A; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit.
 
  
 0.790
ADW18756.1
Sulfur relay protein, TusE/DsrC/DsvC family; COGs: COG2920 Dissimilatory sulfite reductase (desulfoviridin) gamma subunit; InterPro IPR007453; KEGG: dak:DaAHT2_2041 sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC family protein; PRIAM: Hydrogensulfite reductase; SPTR: Sulfur relay protein, TusE/DsrC/DsvC family; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC like protein; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family.
 
 
 
 0.780
ADW16483.1
Putative sulfite reductase-associated electron transfer protein DsrM; COGs: COG2181 Nitrate reductase gamma subunit; InterPro IPR001412: IPR003816; KEGG: dps:DP3075 hypothetical protein; PFAM: Nitrate reductase gamma subunit; SPTR: Hypothetical membrane protein; PFAM: Nitrate reductase gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit.
 
 
 0.779
dsrB
COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterProIPR017896: IPR005117: IPR006067: IPR017900: IPR 011808; KEGG: dps:DP0798 dissimilatory sulfite reductase, beta subunit (DsrB); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; PRIAM: Hydrogensulfite reductase; SPTR: Dissimilatory sulfite reductase subunit B; TIGRFAM: sulfite reductase, dissimilatory-type beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like [...]
 
  
 0.773
ADW16565.1
Protein of unknown function DUF162; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: ppd:Ppro_3136 hypothetical protein; PFAM: protein of unknown function DUF162; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised ACR, YkgG family COG1556.
 
 
 0.736
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.