STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17894.1COGs: COG3259 Coenzyme F420-reducing hydrogenase alpha subunit; InterPro IPR001501: IPR018194; KEGG: dps:DP1013 methylviologen-reducing hydrogenase, alpha chain; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Probable methylviologen-reducing hydrogenase, alpha chain; PFAM: Nickel-dependent hydrogenase. (449 aa)    
Predicted Functional Partners:
ADW17893.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG1941 Coenzyme F420-reducing hydrogenase gamma subunit; InterPro IPR006137: IPR018486; KEGG: dps:DP1012 methyl viologen-reducing hydrogenase, gamma chain; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: Related to methyl viologen-reducing hydrogenase, gamma chain; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.983
ADW17753.1
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352: IPR001041: IPR019574: IPR004108: IPR 003149: IPR017896: IPR017900: IPR000283; KEGG: dma:DMR_07830 putative Fe hydrogenase; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Putative Fe hydrogenase; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulf [...]
   
 
 0.951
ADW16206.1
COGs: COG1941 Coenzyme F420-reducing hydrogenase gamma subunit; InterPro IPR006137; KEGG: apo:Arcpr_1551 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.940
ADW18217.1
NAD(P)-dependent nickel-iron dehydrogenase subunit HoxY; COGs: COG1941 Coenzyme F420-reducing hydrogenase gamma subunit; InterPro IPR006137; KEGG: dps:DP2211 hydrogenase, small chain; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: Probable hydrogenase, small chain; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.932
ADW17752.1
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR011538: IPR019554: IPR019575: IPR017896: IPR 017900; KEGG: dma:DMR_07840 putative NAD-reducing hydrogenase subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: Putative NAD-reducing hydrogenase subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4 [...]
   
 
 0.911
ADW18273.1
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR017900: IPR001949: IPR017896: IPR011538: IPR 019554: IPR019575; KEGG: pth:PTH_2648 NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit; PFAM: NADH-ubiquinone ox [...]
   
 
 0.910
ADW18215.1
NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR001949: IPR011538: IPR019554: IPR019575; KEGG: sus:Acid_5018 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd [...]
   
 
 0.907
ADW17889.1
COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: dps:DP1008 coenzyme F420 hydrogenase, delta subunit; PFAM: peptidase M52 hydrogen uptake protein; SPTR: Related to coenzyme F420 hydrogenase, delta subunit; TIGRFAM: hydrogenase maturation protease; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease.
 
  
 0.865
ADW17892.1
COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: dps:DP1011 methyl-viologen-reducing hydrogenase, delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; SPTR: Methyl-viologen-reducing hydrogenase, delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
 
  
 0.812
ADW17891.1
Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR003953: IPR013027: IPR000103: IPR017896: IPR 017900; KEGG: dps:DP1010 heterodisulfide reductase, subunit A; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Related to heterodisulfide reductase, subunit A; PFAM: Pyridine nucleotide-disulphide oxidoreductase; FAD binding domain; 4Fe-4S binding domain.
 
  
 0.795
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.