STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17899.1Hydrogenase expression/formation protein HypE; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR011854: IPR000728: IPR010918; KEGG: dps:DP0580 hydrogenase accessory protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; SPTR: Probable hydrogenase accessory protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE. (338 aa)    
Predicted Functional Partners:
ADW17898.1
Hydrogenase expression/formation protein HypD; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: dps:DP0579 hydrogenase accessory protein HypD; PFAM: hydrogenase formation HypD protein; SPTR: Probable hydrogenase accessory protein HypD; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.
 
 0.999
ADW17896.1
(NiFe) hydrogenase maturation protein HypF; COGs: COG0068 Hydrogenase maturation factor; InterProIPR004421: IPR001792: IPR011125: IPR006070: IPR 017968; KEGG: dps:DP0577 hydrogenase accessory protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; SPTR: Probable hydrogenase accessory protein HypF; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF.
 
 
 0.996
ADW17897.1
Hydrogenase assembly chaperone hypC/hupF; COGs: COG0298 Hydrogenase maturation factor; InterPro IPR001109: IPR019812; KEGG: dps:DP0578 hydrogenase accessory protein HypC; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); SPTR: Probable hydrogenase accessory protein HypC; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF.
 
 
 0.996
ADW17901.1
Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR003495: IPR012202; KEGG: dps:DP0583 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Probable hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.
 
  
 0.994
ADW17900.1
COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); InterPro IPR000688; KEGG: dps:DP0582 hydrogenase accessory protein HypA; PFAM: hydrogenase expression/synthesis HypA; SPTR: Probable hydrogenase accessory protein HypA; PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA.
 
  
 0.943
ADW17937.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501: IPR018194; KEGG: mag:amb1114 Ni,Fe-hydrogenase I large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase.
 
   
 0.811
ADW19374.1
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: dsa:Desal_2300 methylenetetrahydrofolate reductase (NAD(P)H); PFAM: methylenetetrahydrofolate reductase; PRIAM: Methylenetetrahydrofolate reductase (NAD(P)H); SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase.
     
 0.784
ADW16487.1
Selenium metabolism protein YedF; InterPro IPR019870: IPR001455; KEGG: pca:Pcar_0303 redox protein, regulator of disulfide bond formation; PFAM: SirA-like domain-containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA-like protein; DsrE/DsrF-like family; TIGRFAM: selenium metabolism protein YedF.
     
 0.767
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
      
 0.764
ADW18399.1
COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492: IPR013384; KEGG: pca:Pcar_1148 flagellar hook-filament junction protein; PFAM: flagellin domain protein; SPTR: Flagellin-like; TIGRFAM: flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3.
      
 0.764
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.