Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADW17900.1COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); InterPro IPR000688; KEGG: dps:DP0582 hydrogenase accessory protein HypA; PFAM: hydrogenase expression/synthesis HypA; SPTR: Probable hydrogenase accessory protein HypA; PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA. (128 aa)    
Predicted Functional Partners:
ADW17901.1
Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR003495: IPR012202; KEGG: dps:DP0583 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Probable hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.
 
 
 0.988
ADW19453.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501: IPR018194; KEGG: dar:Daro_3971 nickel-dependent hydrogenase, large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Nickel-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase.
 
 
 0.874
ADW17899.1
Hydrogenase expression/formation protein HypE; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR011854: IPR000728: IPR010918; KEGG: dps:DP0580 hydrogenase accessory protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; SPTR: Probable hydrogenase accessory protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE.
 
  
 0.871
ADW17897.1
Hydrogenase assembly chaperone hypC/hupF; COGs: COG0298 Hydrogenase maturation factor; InterPro IPR001109: IPR019812; KEGG: dps:DP0578 hydrogenase accessory protein HypC; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); SPTR: Probable hydrogenase accessory protein HypC; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF.
 
  
 0.859
ADW17898.1
Hydrogenase expression/formation protein HypD; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: dps:DP0579 hydrogenase accessory protein HypD; PFAM: hydrogenase formation HypD protein; SPTR: Probable hydrogenase accessory protein HypD; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.
 
  
 0.830
ADW17896.1
(NiFe) hydrogenase maturation protein HypF; COGs: COG0068 Hydrogenase maturation factor; InterProIPR004421: IPR001792: IPR011125: IPR006070: IPR 017968; KEGG: dps:DP0577 hydrogenase accessory protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; SPTR: Probable hydrogenase accessory protein HypF; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF.
 
   
 0.817
ADW17937.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501: IPR018194; KEGG: mag:amb1114 Ni,Fe-hydrogenase I large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase.
 
 
 0.816
ADW17217.1
ATPase-like, ParA/MinD; COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR019591: IPR000808; KEGG: dps:DP2935 hypothetical protein; PFAM: ATPase-like, ParA/MinD; SPTR: Conserved hypothetical membrane protein; PFAM: ParA/MinD ATPase like; Anion-transporting ATPase.
   
   0.710
ADW18777.1
Capsular exopolysaccharide family; COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR005702; KEGG: dak:DaAHT2_1741 capsular exopolysaccharide family; PRIAM: Non-specific protein-tyrosine kinase; SPTR: Capsular exopolysaccharide family; TIGRFAM: capsular exopolysaccharide family; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: capsular exopolysaccharide family.
   
   0.710
ADW18372.1
COGs: COG1843 Flagellar hook capping protein; InterPro IPR005648; KEGG: pca:Pcar_1185 flagellar hook initiation protein FlgD; PFAM: flagellar hook capping protein; SPTR: Flagellar hook initiation protein FlgD; PFAM: Flagellar hook capping protein.
    
   0.600
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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