Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADW17901.1Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392: IPR003495: IPR012202; KEGG: dps:DP0583 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: Probable hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. (236 aa)    
Predicted Functional Partners:
ADW17898.1
Hydrogenase expression/formation protein HypD; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: dps:DP0579 hydrogenase accessory protein HypD; PFAM: hydrogenase formation HypD protein; SPTR: Probable hydrogenase accessory protein HypD; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.
 
  
 0.990
ADW17900.1
COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); InterPro IPR000688; KEGG: dps:DP0582 hydrogenase accessory protein HypA; PFAM: hydrogenase expression/synthesis HypA; SPTR: Probable hydrogenase accessory protein HypA; PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA.
 
 
 0.988
ADW17897.1
Hydrogenase assembly chaperone hypC/hupF; COGs: COG0298 Hydrogenase maturation factor; InterPro IPR001109: IPR019812; KEGG: dps:DP0578 hydrogenase accessory protein HypC; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); SPTR: Probable hydrogenase accessory protein HypC; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF.
 
  
 0.975
ADW17899.1
Hydrogenase expression/formation protein HypE; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR011854: IPR000728: IPR010918; KEGG: dps:DP0580 hydrogenase accessory protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; SPTR: Probable hydrogenase accessory protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE.
 
  
 0.973
ADW17896.1
(NiFe) hydrogenase maturation protein HypF; COGs: COG0068 Hydrogenase maturation factor; InterProIPR004421: IPR001792: IPR011125: IPR006070: IPR 017968; KEGG: dps:DP0577 hydrogenase accessory protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; SPTR: Probable hydrogenase accessory protein HypF; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF.
 
   
 0.948
ADW19451.1
COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterProIPR019546: IPR006137: IPR001821: IPR006311: IPR 017909; KEGG: mag:amb1650 Ni,Fe-hydrogenase I small subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Twin-arginine translocation pathway, signal sequence, subgroup; PRIAM: Hydrogenase (acceptor); SPTR: Ni,Fe-hydrogenase I small subunit; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; hydrogenase (NiFe) small subunit (hydA).
 
  
 0.866
ADW16214.1
COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: mxa:MXAN_3831 FKBP-type peptidylprolyl cis-trans isomerase SlyD; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
    
 
 0.821
ADW19465.1
Methyltransferase type 11; InterPro IPR013216; KEGG: dol:Dole_1540 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11; PFAM: Methyltransferase domain.
   
 
 0.795
ADW17938.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR006137: IPR001821; KEGG: dal:Dalk_2280 Ni,Fe-hydrogenase I small subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: Ni,Fe-hydrogenase I small subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA).
 
  
 0.785
ADW19334.1
COGs: COG3261 Ni Fe-hydrogenase III large subunit; KEGG: dps:DP1043 hydrogenase, component E-formate hydrogenlyase subunit 5; SPTR: Related to hydrogenase, component E-formate hydrogenlyase subunit 5; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit.
   
 
 0.783
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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