Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17904.1Uncharacterized protein family UPF0324; InterPro IPR018383; KEGG: tye:THEYE_A0244 hypothetical membrane protein; PFAM: Uncharacterised protein family UPF0324; SPTR: Hypothetical membrane protein; PFAM: Conserved hypothetical protein 698. (590 aa)    
Predicted Functional Partners:
ADW17905.1
KEGG: dvm:DvMF_2093 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.768
dsrB
COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterProIPR017896: IPR005117: IPR006067: IPR017900: IPR 011808; KEGG: dps:DP0798 dissimilatory sulfite reductase, beta subunit (DsrB); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; PRIAM: Hydrogensulfite reductase; SPTR: Dissimilatory sulfite reductase subunit B; TIGRFAM: sulfite reductase, dissimilatory-type beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like [...]
 
     0.696
ADW18174.1
Permease; COGs: COG0730 permease; KEGG: sfu:Sfum_3289 permeases-like; SPTR: Permeases-like; PFAM: Sulfite exporter TauE/SafE.
 
   
 0.658
dsrA
COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterPro IPR017896: IPR006067: IPR011806; KEGG: dps:DP0797 dissimilatory sulfite reductase, alpha subunit (DsrA); PFAM: nitrite and sulphite reductase 4Fe-4S region; PRIAM: Hydrogensulfite reductase; SPTR: Dissimilatory sulfite reductase subunit A; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit.
 
     0.658
ADW18173.1
Protein of unknown function DUF81; InterPro IPR002781; KEGG: sfu:Sfum_3290 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: Putative uncharacterized protein; PFAM: Sulfite exporter TauE/SafE.
 
   
 0.600
ADW17630.1
Protein of unknown function DUF81; InterPro IPR002781; KEGG: dma:DMR_10850 hypothetical membrane protein; PFAM: protein of unknown function DUF81; SPTR: Putative uncharacterized protein; PFAM: Sulfite exporter TauE/SafE.
 
   
 0.578
ADW17447.1
Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: adg:Adeg_2056 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
  
    0.576
ADW17902.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR003661: IPR003594: IPR013656: IPR004358: IPR 005467; KEGG: dba:Dbac_2654 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Pro [...]
       0.555
ADW17903.1
Two component transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789: IPR003593: IPR002078: IPR002114; KEGG: dba:Dbac_2653 putative two component, sigma54 specific, transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; SMART: response regulator receiver; AAA ATPase; SPTR: Putative two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Sigma-54 inter [...]
       0.511
ADW19143.1
KEGG: dak:DaAHT2_2066 hypothetical protein; SPTR: HEAT.
 
     0.500
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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