STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
trmLtRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (157 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
       0.687
ADW17921.1
23S rRNA m(2)A-2503 methyltransferase; COGs: COG0820 Fe-S-cluster redox enzyme; InterPro IPR004383: IPR006638: IPR007197; KEGG: dps:DP1935 hypothetical protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Ribosomal RNA large subunit methyltransferase N; TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM enzyme, Cfr family.
     
 0.606
ADW17928.1
COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR018022: IPR002627; KEGG: dak:DaAHT2_0798 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA delta(2)-isopentenylpyrophosphate transferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: IPP transferase; TIGRFAM: tRNA isopentenyltransferase (miaA).
     
 0.554
ADW17922.1
Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638: IPR007197; KEGG: dak:DaAHT2_0796 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
       0.551
ADW19277.1
COGs: COG0149 Triosephosphate isomerase; InterPro IPR000652: IPR020861; KEGG: dak:DaAHT2_0037 triosephosphate isomerase; PFAM: triosephosphate isomerase; PRIAM: Triose-phosphate isomerase; SPTR: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase; PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase.
      0.521
ADW18183.1
Trigger factor; COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR005215: IPR008881: IPR001179: IPR008880; KEGG: dak:DaAHT2_1304 trigger factor; PFAM: trigger factor domain-containing protein; peptidylprolyl isomerase FKBP-type; SPTR: Trigger factor; TIGRFAM: trigger factor; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Bacterial trigger factor protein (TF); Bacterial trigger factor protein (TF) C-terminus; TIGRFAM: trigger factor.
 
    0.517
ADW17769.1
Protein of unknown function DUF163; COGs: COG1576 conserved hypothetical protein; InterPro IPR003742; KEGG: dak:DaAHT2_0704 protein of unknown function DUF163; PFAM: protein of unknown function DUF163; SPTR: Putative uncharacterized protein; PFAM: Predicted SPOUT methyltransferase; TIGRFAM: rRNA large subunit m3Psi methyltransferase RlmH.
  
   
 0.514
ADW16774.1
Sun protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR004573: IPR006027: IPR001678: IPR018314; KEGG: dak:DaAHT2_2304 sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Fmu, rRNA SAM-dependent methyltransferase; TIGRFAM: sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB.
  
  
 0.455
ADW17927.1
Hypothetical protein; KEGG: dak:DaAHT2_0806 helix-hairpin-helix motif protein; SPTR: Helix-hairpin-helix motif.
       0.420
ADW17925.1
COGs: COG0527 Aspartokinase; InterProIPR005260: IPR001341: IPR001048: IPR002912: IPR 018042; KEGG: dak:DaAHT2_0808 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
     
 0.419
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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