Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17937.1COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501: IPR018194; KEGG: mag:amb1114 Ni,Fe-hydrogenase I large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase. (502 aa)    
Predicted Functional Partners:
ADW17938.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR006137: IPR001821; KEGG: dal:Dalk_2280 Ni,Fe-hydrogenase I small subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: Ni,Fe-hydrogenase I small subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA).
 0.999
ADW19451.1
COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterProIPR019546: IPR006137: IPR001821: IPR006311: IPR 017909; KEGG: mag:amb1650 Ni,Fe-hydrogenase I small subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Twin-arginine translocation pathway, signal sequence, subgroup; PRIAM: Hydrogenase (acceptor); SPTR: Ni,Fe-hydrogenase I small subunit; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; hydrogenase (NiFe) small subunit (hydA).
 0.999
ADW16948.1
Putative adenylylsulfate reductase-associated electron transfer protein QmoB; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR003953: IPR003813: IPR013027: IPR017900: IPR 017896; KEGG: dps:DP1107 fusion protein of heterodisulfide reductase, subunit A (HdrA) and hydrogenase, delta subunit (HydD); PFAM: methyl-viologen-reducing hydrogenase delta subunit; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: Probable fusion protein of heterodisulfide reductase, subunit A (HdrA) and hydrogenase, delta subunit (HydD); PFAM: M [...]
  
 
 0.929
ADW17936.1
COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: mag:amb1113 Ni,Fe-hydrogenase maturation factor; PFAM: peptidase M52 hydrogen uptake protein; SPTR: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease.
 
  
 0.929
ADW19453.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501: IPR018194; KEGG: dar:Daro_3971 nickel-dependent hydrogenase, large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: Nickel-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase.
  
  
 
0.924
ADW17514.1
COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; Contains Selenocysteine; InterPro IPR017896: IPR006076: IPR003813: IPR017900; KEGG: dal:Dalk_1624 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; FAD dependent oxidoreductase; SPTR: Methyl-viologen-reducing hydrogenase delta subunit; manually curated; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; 4Fe-4S binding domain; FAD dependent oxidoreductase.
  
 
 0.909
dsrA
COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterPro IPR017896: IPR006067: IPR011806; KEGG: dps:DP0797 dissimilatory sulfite reductase, alpha subunit (DsrA); PFAM: nitrite and sulphite reductase 4Fe-4S region; PRIAM: Hydrogensulfite reductase; SPTR: Dissimilatory sulfite reductase subunit A; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit.
     
 0.902
dsrB
COGs: COG2221 Dissimilatory sulfite reductase (desulfoviridin) alpha and beta subunits; InterProIPR017896: IPR005117: IPR006067: IPR017900: IPR 011808; KEGG: dps:DP0798 dissimilatory sulfite reductase, beta subunit (DsrB); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; PRIAM: Hydrogensulfite reductase; SPTR: Dissimilatory sulfite reductase subunit B; TIGRFAM: sulfite reductase, dissimilatory-type beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like [...]
     
 0.902
ADW19454.1
COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: etr:ETAE_2363 predicted maturation element for hydrogenase 2; PFAM: peptidase M52 hydrogen uptake protein; SPTR: Hydrogenase expression/formation protein; TIGRFAM: hydrogenase maturation protease; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease.
 
 
 0.878
ADW17898.1
Hydrogenase expression/formation protein HypD; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: dps:DP0579 hydrogenase accessory protein HypD; PFAM: hydrogenase formation HypD protein; SPTR: Probable hydrogenase accessory protein HypD; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD.
 
 
 0.842
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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