close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17947.1Protein of unknown function DUF178; COGs: COG1427 periplasmic solute-binding protein; InterPro IPR003773; KEGG: dak:DaAHT2_0569 protein of unknown function DUF178; PFAM: protein of unknown function DUF178; SPTR: Putative uncharacterized protein; PFAM: Putative periplasminc binding protein (DUF178). (274 aa)    
Predicted Functional Partners:
ADW17950.1
Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR020050: IPR006638: IPR007197: IPR005244; KEGG: dak:DaAHT2_0566 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; PFAM: Radical SAM superfamily; TIGRFAM: putative menaquinone biosynthesis protein, SCO4494 family; radical SAM domain protein, CofH subfamily.
 
  
 0.995
ADW17949.1
Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR020050: IPR007197: IPR005244; KEGG: dak:DaAHT2_0567 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family.
 
   
 0.960
ADW17944.1
COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR000537; KEGG: dak:DaAHT2_0572 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase.
 
   
 0.940
ADW17945.1
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR004507: IPR003382; KEGG: dak:DaAHT2_0571 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; SPTR: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases.
 
   
 0.914
ADW18913.1
Hypothetical protein; COGs: COG2107 periplasmic solute-binding protein; KEGG: ppd:Ppro_3279 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Putative periplasminc binding protein (DUF178).
 
   
 0.857
ADW17948.1
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dak:DaAHT2_0568 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
 
     0.852
ADW19100.1
COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: dak:DaAHT2_2547 UbiD family decarboxylase; PFAM: Carboxylyase-related protein; SPTR: UbiD family decarboxylase; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family.
 
   
 0.829
ADW18324.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR003099: IPR002912; KEGG: dps:DP2275 P-protein; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Prephenate dehydrogenase; SPTR: Related to P-protein; PFAM: Prephenate dehydratase; Prephenate dehydrogenase; ACT domain.
    
  0.824
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
    
  0.823
ADW17569.1
COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterProIPR006221: IPR017926: IPR000991: IPR006220: IPR 011702: IPR001317; KEGG: dps:DP1620 para-aminobenzoate/anthranilate synthase glutamine amidotransferase, component II; PFAM: glutamine amidotransferase class-I; SPTR: Probable para-aminobenzoate/anthranilate synthase glutamine amidotransferase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase.
    
  0.815
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (24%) [HD]