Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
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ADW17948.1Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dak:DaAHT2_0568 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family. (407 aa)    
Predicted Functional Partners:
ADW17950.1
Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR020050: IPR006638: IPR007197: IPR005244; KEGG: dak:DaAHT2_0566 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; PFAM: Radical SAM superfamily; TIGRFAM: putative menaquinone biosynthesis protein, SCO4494 family; radical SAM domain protein, CofH subfamily.
 
  
  0.986
ADW18914.1
Futalosine nucleosidase; COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845: IPR019963; KEGG: dak:DaAHT2_0723 futalosine nucleosidase; PFAM: purine or other phosphorylase family 1; SPTR: Futalosine nucleosidase; TIGRFAM: futalosine nucleosidase; PFAM: Phosphorylase superfamily; TIGRFAM: futalosine nucleosidase.
 
  
 0.934
ADW17949.1
Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR020050: IPR007197: IPR005244; KEGG: dak:DaAHT2_0567 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family.
 
     0.869
ADW17947.1
Protein of unknown function DUF178; COGs: COG1427 periplasmic solute-binding protein; InterPro IPR003773; KEGG: dak:DaAHT2_0569 protein of unknown function DUF178; PFAM: protein of unknown function DUF178; SPTR: Putative uncharacterized protein; PFAM: Putative periplasminc binding protein (DUF178).
 
     0.848
ADW17944.1
COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR000537; KEGG: dak:DaAHT2_0572 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase.
 
     0.743
ADW17945.1
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR004507: IPR003382; KEGG: dak:DaAHT2_0571 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; SPTR: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases.
 
   
 0.728
ADW17946.1
Demethylmenaquinone methyltransferase; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR004033; KEGG: dak:DaAHT2_0570 ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; SPTR: Ubiquinone/menaquinone biosynthesis methyltransferase; TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: ubiE/COQ5 methyltransferase family; TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases.
       0.648
ADW17943.1
KEGG: dak:DaAHT2_0614 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3108).
       0.638
ADW17951.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284: IPR007127: IPR009042: IPR007627: IPR 007624: IPR007630: IPR000943; KEGG: dps:DP2503 RNA polymerase sigma factor (RpoD); PFAM: sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 factor, region 1.1; Sigma-70 region 3; Sigma- [...]
       0.554
ADW19076.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
  
  
 0.531
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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