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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ADW17950.1Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR020050: IPR006638: IPR007197: IPR005244; KEGG: dak:DaAHT2_0566 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative uncharacterized protein; PFAM: Radical SAM superfamily; TIGRFAM: putative menaquinone biosynthesis protein, SCO4494 family; radical SAM domain protein, CofH subfamily. (364 aa)    
Predicted Functional Partners:
ADW17947.1
Protein of unknown function DUF178; COGs: COG1427 periplasmic solute-binding protein; InterPro IPR003773; KEGG: dak:DaAHT2_0569 protein of unknown function DUF178; PFAM: protein of unknown function DUF178; SPTR: Putative uncharacterized protein; PFAM: Putative periplasminc binding protein (DUF178).
 
  
 0.995
ADW17948.1
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dak:DaAHT2_0568 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
 
  
  0.986
ADW17944.1
COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371: IPR000537; KEGG: dak:DaAHT2_0572 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase.
 
   
 0.934
ADW17945.1
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR004507: IPR003382; KEGG: dak:DaAHT2_0571 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; SPTR: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases.
   
 0.865
ADW17949.1
Radical SAM domain protein; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR020050: IPR007197: IPR005244; KEGG: dak:DaAHT2_0567 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family.
 
 
  
0.847
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.839
ADW18913.1
Hypothetical protein; COGs: COG2107 periplasmic solute-binding protein; KEGG: ppd:Ppro_3279 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Putative periplasminc binding protein (DUF178).
 
   
 0.819
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.813
ADW19100.1
COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: dak:DaAHT2_2547 UbiD family decarboxylase; PFAM: Carboxylyase-related protein; SPTR: UbiD family decarboxylase; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family.
 
     0.789
ADW18072.1
Thiamine biosynthesis protein ThiS; InterPro IPR010035: IPR003749; KEGG: pth:PTH_0639 sulfur transfer protein; PFAM: thiamineS protein; SPTR: Sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
  
    0.764
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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