STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17980.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (462 aa)    
Predicted Functional Partners:
ADW16817.1
Chromosomal replication initiator protein DnaA; COGs: COG0593 ATPase involved in DNA replication initiation; InterPro IPR013317: IPR013159: IPR001957: IPR020591; KEGG: dps:DP0278 chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication initiator DnaA; Chromosomal replication initiator DnaA domain; SMART: Chromosomal replication initiator DnaA domain; SPTR: Chromosomal replication initiator protein dnaA; TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA.
 
 
 
 0.950
ADW19068.1
COGs: COG0358 DNA primase; InterProIPR002694: IPR013264: IPR006171: IPR019475: IPR 006154: IPR006295; KEGG: dak:DaAHT2_2321 DNA primase; PFAM: DNA primase catalytic core domain; TOPRIM domain-containing protein; DNA primase, DnaB-helicase binding domain; SMART: Toprim sub domain-containing protein; SPTR: DNA primase; TIGRFAM: DNA primase; PFAM: Toprim domain; DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; DnaB-helicase binding domain of primase; TIGRFAM: DNA primase, catalytic core.
 
 
 0.944
ADW17116.1
Hypothetical protein; COGs: COG0305 Replicative DNA helicase; InterPro IPR007694; KEGG: ade:Adeh_1793 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: DnaB-like helicase C terminal domain.
  
  
 
0.916
ADW16398.1
P4 alpha zinc-binding domain protein; COGs: COG0358 DNA primase; InterPro IPR013237; KEGG: dps:DP1572 hypothetical protein; PFAM: P4 alpha zinc-binding domain protein; SPTR: Putative uncharacterized protein; PFAM: CHC2 zinc finger.
  
 
 0.883
ADW19202.1
IstB domain protein ATP-binding protein; COGs: COG1484 DNA replication protein; InterPro IPR013690: IPR002611: IPR003593; KEGG: psa:PST_0581 ISPsy14, transposition helper protein; PFAM: IstB domain protein ATP-binding protein; IstB ATP binding domain protein; SMART: AAA ATPase; SPTR: ISPsy14, transposition helper protein; PFAM: IstB-like ATP binding protein; IstB-like ATP binding N-terminal.
  
 
 0.882
ADW19263.1
IstB domain protein ATP-binding protein; COGs: COG1484 DNA replication protein; InterPro IPR002611; KEGG: dak:DaAHT2_2591 IstB domain protein ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SPTR: IstB domain protein ATP-binding protein; PFAM: IstB-like ATP binding protein.
  
 
 0.882
ADW16498.1
COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR001270: IPR004622: IPR003593; KEGG: dak:DaAHT2_1885 DNA polymerase III, delta prime subunit; SMART: AAA ATPase; SPTR: DNA polymerase III delta prime subunit; TIGRFAM: DNA polymerase III, delta prime subunit; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit.
 
 
 
 0.757
ADW19212.1
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424: IPR011344; KEGG: dak:DaAHT2_0073 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-strand binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
 
 0.694
ADW18064.1
COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR012763: IPR003959: IPR003593; KEGG: dak:DaAHT2_1248 DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III, subunit gamma and tau.
 
 
 
 0.683
ADW17718.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212: IPR014016: IPR014017; KEGG: dps:DP2879 ATP-dependent DNA helicase UvrD; PFAM: UvrD/REP helicase; SPTR: Probable ATP-dependent DNA helicase, UvrD/REP family; PFAM: UvrD/REP helicase.
 
 
 0.680
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.