STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18017.1COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterProIPR003916: IPR018393: IPR003945: IPR001516: IPR 001750; KEGG: dds:Ddes_1657 proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; SPTR: Proton-translocating NADH-quinone oxidoreductase, chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidore [...] (640 aa)    
Predicted Functional Partners:
ADW17752.1
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR011538: IPR019554: IPR019575: IPR017896: IPR 017900; KEGG: dma:DMR_07840 putative NAD-reducing hydrogenase subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: Putative NAD-reducing hydrogenase subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4 [...]
  
 
 0.995
ADW18013.1
COGs: COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); InterPro IPR018086: IPR001694; KEGG: dds:Ddes_1661 NADH dehydrogenase (quinone); PFAM: respiratory-chain NADH dehydrogenase subunit 1; SPTR: NADH dehydrogenase (Quinone); PFAM: NADH dehydrogenase.
 
 0.995
ADW18016.1
COGs: COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); InterPro IPR001133; KEGG: dds:Ddes_1658 NADH-ubiquinone oxidoreductase chain 4L; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: NADH-quinone oxidoreductase subunit K; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L.
 
 
 0.995
ADW18015.1
COGs: COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); InterPro IPR001457; KEGG: dds:Ddes_1659 NADH-ubiquinone/plastoquinone oxidoreductase chain 6; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; SPTR: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6.
 
 
 0.994
ADW18215.1
NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR001949: IPR011538: IPR019554: IPR019575; KEGG: sus:Acid_5018 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd [...]
  
 
 0.993
ADW18011.1
COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR010218: IPR001268; KEGG: dds:Ddes_1663 NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: NADH-quinone oxidoreductase; TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C.
 
 
 0.986
ADW18009.1
COGs: COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); InterPro IPR018087: IPR000440; KEGG: dds:Ddes_1665 NADH-ubiquinone/plastoquinone oxidoreductase chain 3; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 3; SPTR: NADH-quinone oxidoreductase subunit; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3.
 
 
 0.985
ADW18018.1
COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR003918: IPR010227: IPR001750; KEGG: dds:Ddes_1656 proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
 
 
0.985
ADW18204.1
COGs: COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); InterPro IPR018086: IPR001694; KEGG: abu:Abu_0308 NADH-quinone oxidoreductase, H subunit; PFAM: respiratory-chain NADH dehydrogenase subunit 1; SPTR: NADH dehydrogenase (Quinone); PFAM: NADH dehydrogenase.
 
 0.985
nuoH
NADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
 
 0.984
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.