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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ADW18028.1COGs: COG2145 Hydroxyethylthiazole kinase sugar kinase family; InterPro IPR000417: IPR011144; KEGG: dba:Dbac_0930 hydroxyethylthiazole kinase; PFAM: hydroxyethylthiazole kinase; PRIAM: Hydroxyethylthiazole kinase; SPTR: Hydroxyethylthiazole kinase; PFAM: Hydroxyethylthiazole kinase family; TIGRFAM: hydroxyethylthiazole kinase. (268 aa)    
Predicted Functional Partners:
ADW18029.1
Thiamine-phosphate diphosphorylase; COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: dba:Dbac_0929 thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase.
 
 0.999
ADW18030.1
COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399: IPR013749; KEGG: dba:Dbac_0928 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Phosphomethylpyrimidine kinase; SPTR: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase.
  
 0.999
ADW18076.1
Thiamine-phosphate diphosphorylase; COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: pth:PTH_0643 thiamine monophosphate synthase; PFAM: thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase.
 
 0.999
ADW17945.1
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR004507: IPR003382; KEGG: dak:DaAHT2_0571 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; SPTR: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases.
     
  0.900
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
  
 0.822
ADW18032.1
Binding-protein-dependent transport systems inner membrane component; COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: dba:Dbac_0926 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
       0.797
ADW18031.1
ABC transporter related protein; COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: dba:Dbac_0927 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter.
       0.790
ADW18033.1
NMT1/THI5 like domain protein; COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: dba:Dbac_0925 NMT1/THI5 like domain protein; SPTR: NMT1/THI5 like domain protein; PFAM: NMT1/THI5 like.
       0.779
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.771
ADW18072.1
Thiamine biosynthesis protein ThiS; InterPro IPR010035: IPR003749; KEGG: pth:PTH_0639 sulfur transfer protein; PFAM: thiamineS protein; SPTR: Sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
  
    0.675
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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