STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18029.1Thiamine-phosphate diphosphorylase; COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: dba:Dbac_0929 thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase. (218 aa)    
Predicted Functional Partners:
ADW18028.1
COGs: COG2145 Hydroxyethylthiazole kinase sugar kinase family; InterPro IPR000417: IPR011144; KEGG: dba:Dbac_0930 hydroxyethylthiazole kinase; PFAM: hydroxyethylthiazole kinase; PRIAM: Hydroxyethylthiazole kinase; SPTR: Hydroxyethylthiazole kinase; PFAM: Hydroxyethylthiazole kinase family; TIGRFAM: hydroxyethylthiazole kinase.
 
 0.999
ADW18030.1
COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399: IPR013749; KEGG: dba:Dbac_0928 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Phosphomethylpyrimidine kinase; SPTR: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase.
 
 0.999
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 0.988
ADW18191.1
COGs: COG0611 Thiamine monophosphate kinase; InterPro IPR006283: IPR000728: IPR010918; KEGG: dak:DaAHT2_1499 thiamine-monophosphate kinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; PRIAM: Thiamine-phosphate kinase; SPTR: Thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: thiamine-monophosphate kinase.
   
 0.950
ADW18076.1
Thiamine-phosphate diphosphorylase; COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: pth:PTH_0643 thiamine monophosphate synthase; PFAM: thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase.
  
  
 
0.913
ADW17704.1
COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: dma:DMR_08520 alkaline phosphatase precursor; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase.
    
  0.900
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.895
ADW18072.1
Thiamine biosynthesis protein ThiS; InterPro IPR010035: IPR003749; KEGG: pth:PTH_0639 sulfur transfer protein; PFAM: thiamineS protein; SPTR: Sulfur transfer protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
  
  
 0.860
ADW18047.1
Iron-only hydrogenase maturation protein HydG; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197: IPR010722; KEGG: cbi:CLJ_B3912 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SPTR: Putative thiazole biosynthesis protein; PFAM: Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH.
  
  
 0.835
ADW18074.1
Tyrosine lyase ThiH; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR012726: IPR007197: IPR010722; KEGG: mta:Moth_1664 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SPTR: Thiazole biosynthesis ThiH; TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH.
  
  
 0.835
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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