Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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ADW18049.14Fe-4S ferredoxin iron-sulfur binding domain-containing protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017900: IPR017896: IPR014603; KEGG: drm:Dred_0462 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (266 aa)    
Predicted Functional Partners:
ADW18048.1
COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: dae:Dtox_0170 polysulphide reductase NrfD; PFAM: Polysulphide reductase NrfD; SPTR: Polysulphide reductase NrfD.
 
 0.977
ADW19455.1
COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: sus:Acid_4205 polysulphide reductase, NrfD; PFAM: Polysulphide reductase NrfD; SPTR: Polysulphide reductase, NrfD; PFAM: Polysulphide reductase, NrfD.
 
 0.913
ADW16802.1
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR006311: IPR017900: IPR017909: IPR017896; KEGG: geo:Geob_1593 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
  
  
 
0.907
ADW18296.1
Cyclase family protein; COGs: COG1878 metal-dependent hydrolase; InterPro IPR007325; KEGG: aac:Aaci_2550 cyclase family protein; PFAM: cyclase family protein; SPTR: Cyclase family protein; PFAM: Putative cyclase.
     
  0.900
ADW19350.1
COGs: COG0788 Formyltetrahydrofolate hydrolase; InterPro IPR002912: IPR002376: IPR004810; KEGG: bvu:BVU_3850 formyltetrahydrofolate deformylase; PFAM: formyl transferase domain protein; amino acid-binding ACT domain protein; SPTR: Formyltetrahydrofolate deformylase; TIGRFAM: formyltetrahydrofolate deformylase; PFAM: Formyl transferase; TIGRFAM: formyltetrahydrofolate deformylase.
     
  0.900
ADW16803.1
COGs: COG5557 Polysulphide reductase; InterPro IPR005614; KEGG: geo:Geob_1592 polysulphide reductase NrfD; PFAM: Polysulphide reductase NrfD; SPTR: Polysulphide reductase NrfD.
 
 0.853
ADW17542.1
Periplasmic nitrate reductase subunit NapA apoprotein; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR006311: IPR017909: IPR006963: IPR006656: IPR 006657; KEGG: dap:Dacet_0086 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: periplasmic nitrate reductase, large subunit; Tat (twin-argi [...]
  
 
 0.819
ADW16573.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.816
ADW16228.1
Fumarase; COGs: COG0114 Fumarase; InterProIPR020557: IPR000362: IPR003031: IPR005677: IPR 018951; KEGG: dap:Dacet_2357 fumarate hydratase, class II; PFAM: fumarate lyase; Fumarase C-like; SPTR: Fumarate hydratase, class II; TIGRFAM: fumarate hydratase, class II; PFAM: Lyase; Fumarase C C-terminus; TIGRFAM: fumarate hydratase, class II.
     
  0.800
ADW17373.1
COGs: COG2225 Malate synthase; InterPro IPR011076; KEGG: sti:Sthe_2906 malate synthase A; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: Malate synthase; PFAM: Malate synthase; TIGRFAM: malate synthase A.
     
  0.800
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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