STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18108.1COGs: COG0259 Pyridoxamine-phosphate oxidase; InterPro IPR000659: IPR019740: IPR011576: IPR019576; KEGG: maq:Maqu_0155 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; Pyridoxine 5'-phosphate oxidase, dimerisation-like; PRIAM: Pyridoxal 5'-phosphate synthase; SPTR: Pyridoxine/pyridoxamine 5'-phosphate oxidase; TIGRFAM: pyridoxamine 5'-phosphate oxidase; PFAM: Pyridoxamine 5'-phosphate oxidase; Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; TIGRFAM: pyridoxamine-phosphate oxidase. (212 aa)    
Predicted Functional Partners:
ADW17456.1
Pyridoxine 5'-phosphate synthase; COGs: COG0854 Pyridoxal phosphate biosynthesis protein; InterPro IPR002036: IPR004569: IPR020549; KEGG: dps:DP1605 pyridoxal phosphate biosynthetic protein; PFAM: Pyridoxal phosphate biosynthetic protein PdxJ; protein of unknown function UPF0054; PRIAM: Pyridoxine 5'-phosphate synthase; SPTR: Probable pyridoxal phosphate biosynthetic protein; TIGRFAM: pyridoxal phosphate biosynthetic protein PdxJ; PFAM: Pyridoxal phosphate biosynthesis protein PdxJ; Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family; pyridoxine 5'-phos [...]
  
  
 0.937
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082: IPR006132: IPR006131: IPR006130; KEGG: dak:DaAHT2_2315 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carb [...]
      0.543
ADW18109.1
Hypothetical protein; InterPro IPR016160; KEGG: dsa:Desal_2216 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.539
ADW18110.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166: IPR006094: IPR004113; KEGG: pca:Pcar_2765 glycolate oxidase subunit D; PFAM: FAD linked oxidase domain protein; SPTR: Glycolate oxidase subunit D; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
       0.512
ADW18111.1
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR017900: IPR017896: IPR004017: IPR012257; KEGG: pca:Pcar_2766 Fe-S oxidoreductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Fe-S oxidoreductase; PFAM: Cysteine-rich domain.
       0.501
ADW18112.1
Protein of unknown function DUF2088; COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: gbm:Gbem_0565 hypothetical protein; PFAM: Protein of unknown function DUF2088; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088).
       0.501
ADW18107.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: acp:A2cp1_4171 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Silent information regulator protein Sir2; PFAM: Sir2 family.
  
    0.475
ADW19423.1
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005481: IPR005479: IPR005480: IPR011607: IPR 005483: IPR006275: IPR011761; KEGG: sat:SYN_02589 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-l [...]
 
 
  
 0.471
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.436
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
   
 
 0.419
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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