STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18136.1COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR012779; KEGG: gbm:Gbem_0268 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: Aminopeptidase N; TIGRFAM: aminopeptidase N; PFAM: Domain of unknown function (DUF3458); Peptidase family M1; TIGRFAM: aminopeptidase N, Escherichia coli type. (904 aa)    
Predicted Functional Partners:
ADW18456.1
COGs: COG0260 Leucyl aminopeptidase; InterPro IPR000819: IPR008283; KEGG: dat:HRM2_40450 PepA; PFAM: peptidase M17 leucyl aminopeptidase domain protein; PRIAM: Leucyl aminopeptidase; SPTR: Leucyl aminopeptidase; PFAM: Cytosol aminopeptidase family, catalytic domain; Cytosol aminopeptidase family, N-terminal domain.
  
 0.936
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.850
ADW19122.1
COGs: COG0031 Cysteine synthase; InterPro IPR001926: IPR005856: IPR005859; KEGG: bth:BT_3080 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases.
   
 0.845
ADW17036.1
L-aspartate aminotransferase apoenzyme; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR001176: IPR004838; KEGG: dak:DaAHT2_0356 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
  
 
 0.810
ADW17222.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176: IPR004839: IPR004838; KEGG: dak:DaAHT2_0099 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
  
 
 0.810
ADW16750.1
COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004439: IPR001804: IPR019818; KEGG: hmo:HM1_1471 isocitrate dehydrogenase, nADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; SPTR: Isocitrate dehydrogenase [NADP]; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type.
    
 0.713
ADW16956.1
COGs: COG0244 Ribosomal protein L10; InterPro IPR001790; KEGG: dps:DP1115 50S ribosomal protein L10; PFAM: ribosomal protein L10; SPTR: 50S ribosomal protein L10; PFAM: Ribosomal protein L10.
   
 0.684
ADW17171.1
Hypothetical protein; InterPro IPR000719; KEGG: dsa:Desal_2316 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 0.679
ADW16967.1
COGs: COG0089 Ribosomal protein L23; InterPro IPR013025; KEGG: dps:DP1126 50S ribosomal protein L23; PFAM: Ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23; PFAM: Ribosomal protein L23.
    
  0.676
ADW16974.1
COGs: COG0198 Ribosomal protein L24; InterPro IPR005824: IPR003256: IPR005825; KEGG: dps:DP1135 50S ribosomal protein L24; PFAM: KOW domain protein; SMART: KOW domain protein; SPTR: 50S ribosomal protein L24; TIGRFAM: ribosomal protein L24; PFAM: KOW motif; TIGRFAM: ribosomal protein L24, bacterial/organelle.
    
  0.676
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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