STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW18152.1COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR013656: IPR003661: IPR 003594; KEGG: dde:Dde_3535 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (407 aa)    
Predicted Functional Partners:
ADW18153.1
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR020441: IPR002078: IPR001789: IPR002197: IPR 003593; KEGG: dps:DP0953 Ntr family two-component response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Probable two-component system response regulator (Ntr family); PFAM: Response regulator receiver domain; Bacterial regu [...]
   0.915
ADW18151.1
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: dps:DP0955 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Probable iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase.
 
     0.835
ADW16898.1
Adenylate/guanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR001054: IPR018297; KEGG: bja:blr2288 two-component hybrid sensor and regulator; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SPTR: Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain.
  
   0.788
ADW17757.1
Fe-S cluster domain protein; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR007202: IPR017896: IPR017900; KEGG: sfu:Sfum_1846 putative PAS/PAC sensor protein; PFAM: Fe-S cluster domain protein; SPTR: Putative PAS/PAC sensor protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Putative Fe-S cluster.
 
      0.732
ADW19127.1
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR000160: IPR018228; KEGG: cyh:Cyan8802_1169 response regulator receiver modulated diguanylate cyclase; PFAM: response regulator receiver; GGDEF domain containing protein; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: Response regulator receiver modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
     0.690
ADW18405.1
Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789: IPR003607: IPR006674; KEGG: wsu:WS1726 signal transduction response regulator; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region; SPTR: SIGNAL TRANSDUCTION RESPONSE REGULATOR; PFAM: HD domain; Response regulator receiver domain.
 
   0.644
ADW16797.1
PAS sensor protein; InterPro IPR013767: IPR000014; KEGG: met:M446_4819 putative PAS/PAC sensor protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
 
  
   0.641
ADW19008.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dol:Dole_1350 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
   0.641
ADW17006.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dal:Dalk_1498 histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Histidine kinase; PFAM: Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
 
 0.636
ADW19004.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dol:Dole_1357 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
   0.633
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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