Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADW18176.1COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dat:HRM2_16240 hypothetical protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Putative uncharacterized protein; PFAM: Response regulator receiver domain. (123 aa)    
Predicted Functional Partners:
ADW18177.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR000014: IPR005467: IPR000700: IPR 013767: IPR003661: IPR003594: IPR001610; KEGG: sfu:Sfum_2763 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; SPTR: PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine [...]
 
 
   0.877
ADW18175.1
PAS sensor protein; InterProIPR000014: IPR000700: IPR003018: IPR013656: IPR 003661: IPR001610; KEGG: dat:HRM2_42110 GGDEF domain family protein; PFAM: GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: GAF domain protein; PAC repeat-containing protein; histidine kinase A domain protein; SPTR: GGDEF domain family protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
 
 
 0.791
ADW18178.1
KEGG: dal:Dalk_2528 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.704
ADW16315.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: gme:Gmet_3472 response regulator receiver domain-containing protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
  
     0.696
ADW18189.1
COGs: COG2453 protein-tyrosine phosphatase; InterPro IPR016130: IPR000387: IPR000340: IPR020422; KEGG: dat:HRM2_16250 putative protein phosphatase; PFAM: Dual specificity protein phosphatase; SMART: Dual specificity phosphatase, subgroup, catalytic domain; SPTR: Putative uncharacterized protein; PFAM: Dual specificity phosphatase, catalytic domain.
 
   
 0.660
ADW16654.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR004358: IPR003594; KEGG: sfu:Sfum_0617 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
   0.620
ADW18631.1
Histidine kinase; COGs: COG1639 signal transduction protein; InterProIPR004358: IPR003607: IPR003661: IPR003594: IPR 005467: IPR013976; KEGG: dat:HRM2_30910 fusion protein comosed of N:signal transduction protein - C:ATPase-like osmosensitive K+ channel histidine kinase; PFAM: Metal-dependent hydrolase HDOD; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; metal-dependent phosphohydrolase HD region; SPTR: Fusion protein comosed of N:signal transduction protein-C:ATPase-like o [...]
 
   0.592
ADW19039.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dal:Dalk_0308 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
  
     0.576
ADW16314.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 003594: IPR013767: IPR013655; KEGG: cli:Clim_1831 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; P [...]
 
 
 0.570
ADW16312.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: cli:Clim_1832 putative PAS/PAC sensor protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Putative PAS/PAC sensor protein; PFAM: Response regulator receiver domain.
  
     0.545
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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