STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ppk1Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (737 aa)    
Predicted Functional Partners:
ADW18088.1
Protein of unknown function DUF344; COGs: COG2326 conserved hypothetical protein; InterPro IPR005660: IPR016898; KEGG: dps:DP2743 hypothetical protein; PFAM: protein of unknown function DUF344; SPTR: Putative uncharacterized protein; PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate kinase 2, PA0141 family.
 
  
 0.969
ADW18970.1
DHHA2 domain protein; COGs: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; InterPro IPR001667: IPR004097; KEGG: dak:DaAHT2_0690 DHHA2 domain protein; PFAM: DHHA2 domain protein; phosphoesterase RecJ domain protein; SPTR: DHHA2 domain protein; PFAM: DHH family; DHHA2 domain.
     
  0.900
ADW19307.1
Polyphosphate:AMP phosphotransferase; COGs: COG2326 conserved hypothetical protein; InterPro IPR005660; KEGG: slt:Slit_2953 protein of unknown function DUF344; PFAM: protein of unknown function DUF344; SPTR: Putative uncharacterized protein; PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate:AMP phosphotransferase.
 
   
 0.752
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
  
  
 0.627
ADW17824.1
CHAD domain containing protein; COGs: COG5607 conserved hypothetical protein; InterPro IPR007899; KEGG: pvi:Cvib_0907 CHAD domain-containing protein; PFAM: CHAD domain containing protein; SPTR: CHAD domain containing protein; PFAM: CHAD domain.
 
   
 0.538
ADW18180.1
Conserved hypothetical protein CHP00730; COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: cja:CJA_1346 decarboxylase family protein; PFAM: Conserved hypothetical protein CHP00730; SPTR: Decarboxylase family protein; PFAM: Domain of unknown function (DUF3412); Possible lysine decarboxylase.
       0.481
ADW18462.1
Phosphoribosylformylglycinamidine cyclo-ligase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR000728: IPR010918: IPR004733; KEGG: dak:DaAHT2_1081 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribo [...]
    
 0.467
nifU
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
     
 0.412
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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