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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ADW18185.1COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterProIPR004487: IPR017948: IPR010603: IPR013093: IPR 019489: IPR003593; KEGG: dak:DaAHT2_1302 ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpX; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX). (422 aa)    
Predicted Functional Partners:
ADW18184.1
COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907: IPR018215; KEGG: dps:DP2538 ATP-dependent Clp protease, proteolytic subunit (ClpP); PFAM: peptidase S14 ClpP; PRIAM: Endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP.
 0.999
ADW16386.1
KEGG: aco:Amico_1120 peptidase U35 phage prohead HK97; SPTR: Peptidase U35 phage prohead HK97.
  
 0.976
ADW18186.1
COGs: COG0466 ATP-dependent Lon protease; InterProIPR001984: IPR008268: IPR004815: IPR003111: IPR 003959: IPR003593; KEGG: dak:DaAHT2_1301 ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; PRIAM: Endopeptidase La; SMART: peptidase S16 lon domain protein; AAA ATPase; SPTR: ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: ATP-dependent protease La (LON) domain; ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La.
 
 
 0.908
ADW18183.1
Trigger factor; COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR005215: IPR008881: IPR001179: IPR008880; KEGG: dak:DaAHT2_1304 trigger factor; PFAM: trigger factor domain-containing protein; peptidylprolyl isomerase FKBP-type; SPTR: Trigger factor; TIGRFAM: trigger factor; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Bacterial trigger factor protein (TF); Bacterial trigger factor protein (TF) C-terminus; TIGRFAM: trigger factor.
 
  
 0.851
ADW19471.1
COGs: COG0262 Dihydrofolate reductase; InterPro IPR001796: IPR012259: IPR017925; KEGG: gsu:GSU0571 dihydrofolate reductase; PFAM: dihydrofolate reductase region; PRIAM: Dihydrofolate reductase; SPTR: Dihydrofolate reductase; PFAM: Dihydrofolate reductase.
   
 
 0.841
atpD
ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
 
   
 0.811
ADW18078.1
COGs: COG0225 Peptide methionine sulfoxide reductase; InterPro IPR002569: IPR002579; KEGG: tau:Tola_0999 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; Methionine sulfoxide reductase A; PRIAM: Peptide-methionine (S)-S-oxide reductase., Peptide-methionine (R)-S-oxide reductase; SPTR: Methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; peptide methionine sulfoxide reductase; PFAM: SelR domain; Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase.
  
 
 0.795
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
 0.795
ADW16558.1
Membrane protease FtsH catalytic subunit; COGs: COG0465 ATP-dependent Zn protease; InterProIPR005936: IPR003959: IPR000642: IPR003960: IPR 003593; KEGG: mfa:Mfla_1168 FtsH-2 peptidase; PFAM: peptidase M41; AAA ATPase central domain protein; PRIAM: Microtubule-severing ATPase; SMART: AAA ATPase; SPTR: FtsH-2 peptidase. Metallo peptidase. MEROPS family M41; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH.
   
  
 0.765
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
  
 0.765
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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