Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW18192.1COGs: COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component); InterPro IPR006318: IPR000121: IPR008731: IPR008279; KEGG: pca:Pcar_1929 PEP-protein phosphotransferase system enzyme I; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; SPTR: Phosphoenolpyruvate--protein phosphotransferase; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase. (597 aa)    
Predicted Functional Partners:
ADW18193.1
Phosphocarrier, HPr family; InterPro IPR005698: IPR000032; KEGG: rba:RB8588 phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: Phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
 
 0.999
ADW16690.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: pca:Pcar_1936 phosphotransferase system enzyme IIA, regulates nitrogen metabolism; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: Phosphotransferase system enzyme IIA, regulates nitrogen metabolism; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.872
ADW18191.1
COGs: COG0611 Thiamine monophosphate kinase; InterPro IPR006283: IPR000728: IPR010918; KEGG: dak:DaAHT2_1499 thiamine-monophosphate kinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; PRIAM: Thiamine-phosphate kinase; SPTR: Thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: thiamine-monophosphate kinase.
       0.775
ADW18188.1
Putative two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR020441: IPR002078: IPR001789: IPR003593; KEGG: dat:HRM2_12070 sigma-54 dependent DNA-binding response regulator (fis family protein); PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; SMART: response regulator receiver; AAA ATPase; SPTR: Helix-turn-helix, Fis-type; PFAM: Response regulator receiver domain; Sigma-54 interaction domain.
  
    0.774
ADW18187.1
InterPro IPR005358; KEGG: tai:Taci_1142 protein of unknown function UPF0153; PFAM: protein of unknown function UPF0153; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0153).
       0.773
ADW18189.1
COGs: COG2453 protein-tyrosine phosphatase; InterPro IPR016130: IPR000387: IPR000340: IPR020422; KEGG: dat:HRM2_16250 putative protein phosphatase; PFAM: Dual specificity protein phosphatase; SMART: Dual specificity phosphatase, subgroup, catalytic domain; SPTR: Putative uncharacterized protein; PFAM: Dual specificity phosphatase, catalytic domain.
       0.773
ADW18190.1
COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192: IPR008279; KEGG: dat:HRM2_16260 PpsA4; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: Pyruvate phosphate dikinase PEP/pyruvate-binding; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain.
       0.773
ADW18194.1
KEGG: dps:DP2269 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
ADW19278.1
COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576: IPR015911; KEGG: dps:DP0101 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase.
   
  
 0.653
ADW18195.1
KEGG: mbr:MONBRDRAFT_30710 hypothetical protein; SPTR: Predicted protein.
       0.590
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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